Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12010059 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AITGB3ITGA2BPDK1 | |
| SCHEMBL4027372 | 0.83 | PDK1 (0.39) | MEN1KMT2AMAPK1ITGB3ITGA2B | |
| SCHEMBL11107022 | 0.82 | HDAC1 (0.45) | MEN1KMT2AMAPTITGB3ITGA2B | |
| SCHEMBL24722155 | 0.81 | MAPT (0.44) | MAPTMAPK1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL6865515 | 0.78 | MAPT (0.48) | MAPTGAAMAPK1PDK2HPGD | |
| SCHEMBL12302105 | 0.75 | KMT2A (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27622304 | 0.75 | PIN1 (0.35) | MEN1KMT2AITGB3ITGA2BPDK1 | |
| SCHEMBL4029711 | 0.75 | PIN1 (0.35) | MEN1KMT2AITGB3ITGA2BPDK1 | |
| SCHEMBL2282162 | 0.74 | KMT2A (0.53) | MEN1KMT2AHPGDALDH1A1PIN1 | |
| SCHEMBL4223718 | 0.74 | P2RX7 (0.51) | MAPTHPGDALDH1A1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789039-B1 | S-TRIAZOLYL ALPHA -MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | ARDEA BIOSCIENCES INC (US) | 2012-01-11 | — | — | EP | disclosed |