Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080359 | 0.84 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL14740667 | 0.80 | KMT2A (0.49) | PRMT5WDR77KCNH2 | |
| SCHEMBL10079265 | 0.79 | PRMT5 (0.35) | PRMT5WDR77EPHX1 | |
| SCHEMBL10079261 | 0.78 | PRKCQ (0.43) | PRMT5WDR77 | |
| SCHEMBL10080416 | 0.77 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL10079676 | 0.75 | LTA4H (0.37) | PRMT5WDR77METTL3CHEK1DRD2 | |
| SCHEMBL4953532 | 0.74 | CXCR4 (0.50) | EED | |
| SCHEMBL19314023 | 0.73 | EED (0.48) | PRMT5WDR77METTL3CHEK1EED | |
| SCHEMBL12085509 | 0.73 | CXCR4 (0.40) | PRMT5WDR77METTL3ACP1 | |
| SCHEMBL19377884 | 0.71 | CCNT1 (0.43) | ACP1DRD2KCNH2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |