Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956859 | 0.85 | MAPK1 (0.41) | ALDH1A1LMNAHTTL3MBTL1HSD17B10 | |
| SCHEMBL543687 | 0.84 | KDM4E (0.55) | ALDH1A1LMNAL3MBTL1HSD17B10MAPT | |
| SCHEMBL543700 | 0.81 | SLC7A5 (0.44) | ALDH1A1LMNAHTTHSD17B10MAPT | |
| SCHEMBL10078799 | 0.80 | PDK1 (0.47) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL4687150 | 0.73 | PTGER4 (0.43) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL4715427 | 0.73 | CYP3A4 (0.44) | ALDH1A1HTTL3MBTL1HSD17B10MAPT | |
| SCHEMBL4235473 | 0.72 | KDM4E (0.51) | ALDH1A1LMNAL3MBTL1HSD17B10MAPT | |
| SCHEMBL27655381 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTL3MBTL1HSD17B10 | |
| SCHEMBL13841059 | 0.70 | KDM4E (0.57) | ALDH1A1LMNAL3MBTL1HSD17B10MAPT | |
| SCHEMBL27383653 | 0.69 | KDM4E (0.55) | ALDH1A1LMNAL3MBTL1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110688-B2 | Method for producing indole derivative having piperidine ring | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20100197926-A1 | METHOD FOR PRODUCING INDOLE DERIVATIVE HAVING PIPERIDINE RING | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197926-A1 | METHOD FOR PRODUCING INDOLE DERIVATIVE HAVING PIPERIDINE RING | IDO2, IDO1, TPH2 | ALDH1A1 25/4885LMNA 3226/4885HTT 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.