Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235473 | 0.86 | KDM4E (0.51) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL27655381 | 0.85 | ALDH1A1 (0.40) | PTGER4GAAKDM4EHTTALDH1A1 | |
| SCHEMBL15087345 | 0.79 | PTGER4 (0.50) | PTGER4CDC25BGAAKDM4EHTT | |
| SCHEMBL1560414 | 0.78 | MAPT (0.54) | PTGER4CDC25BGAAKDM4EHTT | |
| SCHEMBL1404238 | 0.77 | LNPEP (0.35) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4687689 | 0.77 | CASP6 (0.54) | MAPTLMNATSHR | |
| SCHEMBL15706239 | 0.76 | CDC25B (0.53) | PTGER4CDC25BGAAKDM4EHTT | |
| SCHEMBL4233674 | 0.76 | HCAR3 (0.40) | CA1CA2CA12CA4CA6 | |
| SCHEMBL3956859 | 0.75 | MAPK1 (0.41) | GAAKDM4EHTTALDH1A1MAPT | |
| SCHEMBL12367380 | 0.75 | CYP3A4 (0.43) | ALDH1A1MAPTTHRBCA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |