Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468215 | 0.83 | APOBEC3A (0.33) | APOBEC3AAPOBEC3GGRM5ALDH1A1MEN1 | |
| SCHEMBL4543357 | 0.82 | TEAD3 (0.43) | ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL6468593 | 0.79 | MEN1 (0.48) | APOBEC3AAPOBEC3GALDH1A1ALDH1A3MEN1 | |
| SCHEMBL24574472 | 0.69 | THRA (0.49) | ALDH1A1ALDH3A1ALDH1A3MEN1GAA | |
| SCHEMBL24574283 | 0.69 | THRA (0.49) | ALDH1A1ALDH3A1ALDH1A3MEN1GAA | |
| SCHEMBL6468545 | 0.68 | FBP1 (0.35) | GAAMAPT | |
| SCHEMBL7487588 | 0.67 | MEN1 (0.55) | APOBEC3AAPOBEC3GGRM5ALDH1A1ALDH1A3 | |
| SCHEMBL16749907 | 0.65 | NPSR1 (0.46) | ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL10080603 | 0.65 | SOAT1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL7035542 | 0.65 | MEN1 (0.52) | APOBEC3AAPOBEC3GGRM5ALDH1A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062229-A1 | A METHOD OF MANUFACTURING (-)-L-(3-HYDROXYPROPYL)-5-[(2R)-2-({2,2,2-TRIFLUOROETHOXY)- PHENOXYETHYL}AMINO)PROPYL]-2,3-DIHYDRO-LH-INDOLE-7-CARBOXAMIDE | ZENTIVA, K.S. (CZ) | 2012-05-18 | — | — | WO | disclosed |