Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615040 | 0.83 | MAPT (0.59) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL17536913 | 0.83 | MAPT (0.59) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL3456619 | 0.83 | MAPT (0.59) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL2021618 | 0.83 | MAPT (0.59) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL18133359 | 0.77 | CYP1A2 (0.61) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL13070418 | 0.77 | MAPT (0.53) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL6311246 | 0.77 | ACHE (0.55) | MAPTL3MBTL1MAOANPC1RAB9A | |
| SCHEMBL17133042 | 0.77 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL17133046 | 0.77 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL6392102 | 0.77 | ALOX15 (0.48) | MAPTALDH1A1KDM4ELMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |