SCHEMBL10084010

SCHEMBL10084010

COc1ccc(S(=O)(=O)ON=C(C#N)c2cccc(C(C#N)=NOS(=O)(=O)c3ccc(CO)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
SIRT2 Q8IXJ6 1/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
ATM Q13315 1/20 0.38
AKR1C3 P42330 1/20 0.38
TAS2R14 Q9NYV8 3/20 0.37
CYP19A1 P11511 1/20 0.37
PKM P14618 2/20 0.37
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
TCF4 P15884 1/20 0.36
CTNNB1 P35222 1/20 0.36
SMPD1 P17405 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15214878 0.92 KMT2A (0.43) KMT2AMEN1ATMCYP19A1PKM
SCHEMBL12727038 0.90 IDO1 (0.40) MAPTSIRT2KMT2AMEN1ATM
SCHEMBL29645031 0.86 PKM (0.43) MAPTSIRT2KMT2AMEN1ATM
SCHEMBL5918261 0.82 EP300 (0.45) MAPTPKMEP300KAT2AKAT2B
SCHEMBL5918260 0.82 EP300 (0.45) MAPTPKMEP300KAT2AKAT2B
SCHEMBL11003138 0.82 NPC1 (0.46) MAPTKMT2AMEN1ATMPKM
SCHEMBL11003125 0.82 NPC1 (0.46) MAPTKMT2AMEN1ATMPKM
SCHEMBL10083960 0.80 TCF4 (0.38) MAPTKMT2AMEN1PKMTCF4
SCHEMBL7781708 0.80 PDE4A (0.47) MAPTKMT2AMEN1TAS2R14LMNA
SCHEMBL7781706 0.80 PDE4A (0.47) MAPTKMT2AMEN1TAS2R14LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389197-B2 Compound, positive resist composition and resist pattern forming method TOKYO OHKA KOGYO CO., LTD. (JP) 2013-03-05 US disclosed
US-8216764-B2 acrylate ester resin having a tertiary alkyl ester-type acid dissociable, dissolution inhibiting group, and acid generator; reducing line width roughness (LWR) and suppressing development of footing which is likely to occur with a substrate having an inorganic antireflection film (inorganic BARC) TOKYO OHKA KOGYO CO., LTD. (JP) 2012-07-10 US disclosed
US-8206887-B2 Positive resist composition and resist pattern forming method TOKYO OHKA KOGYO CO., LTD. (JP) 2012-06-26 US disclosed
US-8105747-B2 Positive resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2012-01-31 US disclosed
US-8062825-B2 Positive resist composition and resist pattern forming method TOKYO OHKA KOGYO CO., LTD. (JP) 2011-11-22 US disclosed
US-8021824-B2 Polymer compound, resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2011-09-20 US disclosed
US-7981588-B2 Negative resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2011-07-19 US disclosed
US-7972762-B2 resist pattern with reduced defects and excellent lithographic characteristics; acrylate ester copolymer obtained by polymerizing an ( alpha -lower alkyl)acrylate ester having tertiary alkyl ester-type acid dissociable dissolution inhibiting group, under a presence of acid TOKYO OHKA KOGYO CO., LTD. (JP) 2011-07-05 US disclosed
US-7964331-B2 Positive resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2011-06-21 US disclosed
US-7943284-B2 Compound, dissolution inhibitor, positive type resist composition, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2011-05-17 US disclosed
US-7504196-B2 Positive resist composition, method for resist pattern formation and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2009-03-17 US disclosed
US-20090068583-A1 resin comprises (2-adamantyloxymethyl)methacrylate monomers which exhibit increased alkali solubility under action of acid, and acid generator such as diphenyliodonium trifluoromethanesulfonate; reduced line edge roughness, improved shape and depth of focus TOKYO OHKA KOGYO CO., LTD. (JP) 2009-03-12 US disclosed
US-20090068588-A1 POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2009-03-12 US disclosed
US-20090047600-A1 high resolution pattern with reduced line edge roughness; increased alkali solubility under action of acid generator TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-19 US disclosed
US-20090042129-A1 POSITIVE RESIST COMPOSITION AND METHOD FOR RESIST PATTERN FORMATION TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-12 US disclosed
US-20090035697-A1 NEGATIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKAKOGYO CO.,LTD. (JP) 2009-02-05 US disclosed
US-20090035691-A1 POSITIVE RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-05 US disclosed
US-20090004598-A1 Resist Composition And Method For Forming Resist Pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2009-01-01 US disclosed
US-20080193871-A1 Positive Resist Composition For Immersion Exposure and Method of Forming Resist Pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2008-08-14 US disclosed
US-20080145784-A1 Positive Resist Composition, Method For Resist Pattern Formation and Compound TOKYO OHKA KOGYO CO., LTD. (JP) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035691-A1 POSITIVE RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND COMPOUND POLR1A, CA1, POLR2A MAPT 3037/4885SIRT2 4450/4885KMT2A 2541/4885
US-20080145784-A1 Positive Resist Composition, Method For Resist Pattern Formation and Compound POLR1A, POLR2A, POLR2B MAPT 3002/4885SIRT2 4516/4885KMT2A 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.