SCHEMBL1009016

SCHEMBL1009016

N=C(N)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
F2 P00734 3/20 0.35
PRSS1 P07477 3/20 0.35
PRSS2 P07478 3/20 0.35
PRSS3 P35030 3/20 0.35
LMNA P02545 1/20 0.35
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4420537 1.00 THRB (0.46) THRBF2PRSS1PRSS2PRSS3
SCHEMBL322433 0.91 THRB (0.33) THRB
SCHEMBL2876518 0.91 THRB (0.33) THRB
SCHEMBL1009774 0.88 THRB (0.32) THRBF2PRSS1PRSS2PRSS3
SCHEMBL6255566 0.88 ALDH1A1 (0.30)
SCHEMBL11005732 0.81
SCHEMBL6577261 0.79
SCHEMBL1556023 0.76 ALDH1A1 (0.30)
SCHEMBL11000094 0.74
SCHEMBL4593915 0.72 THRB (0.59) THRBF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11390726-B2 Method of bonding perfluoroelastomeric materials to a surface GREENE, TWEED TECHNOLOGIES, INC. (US) 2022-07-19 US claimed
US-20210198447-A1 Method of Bonding Perfluoroelastomeric Materials to a Surface GREENE, TWEED OF DELAWARE, INC. 2021-07-01 US claimed
EP-2617738-B1 METHOD OF BONDING PERFLUOROELASTOMERIC MATERIALS TO A SURFACE GREENE TWEED TECH INC (US) 2021-05-05 EP claimed
EP-1587784-B1 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE TWEED INC (US) 2014-10-15 EP claimed
EP-2617738-A1 Method of bonding perfluoroelastomeric materials to a surface GREENE, TWEED OF DELAWARE, INC. (US) 2013-07-24 EP claimed
EP-1730232-B1 FAST CURING FLUOROELASTOMERIC COMPOSITIONS, ADHESIVE FLUOROELASTOMERIC COMPOSITIONS AND METHODS FOR BONDING FLUOROELASTOMERIC COMPOSITIONS GREENE TWEED INC (US) 2010-10-20 EP claimed
JP-2010516864-A 2010-05-20 JP claimed
EP-2115012-A1 METHOD OF BONDING PERFLUOROELASTOMERIC MATERIALS TO A SURFACE GREENE, TWEED OF DELAWARE, INC. (US) 2009-11-11 EP claimed
US-7521510-B2 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC (US) 2009-04-21 US claimed
US-7514506-B2 Fast curing fluoroelastomeric compositions, adhesive fluoroelastomeric compositions and methods for bonding fluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. (US) 2009-04-07 US claimed
EP-1587784-A4 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE TWEED INC (US) 2008-10-29 EP claimed
WO-2008094758-A1 METHOD OF BONDING PERFLUOROELASTOMERIC MATERIALS TO A SURFACE GREENE, TWEED OF DELAWARE, INC. (US) 2008-08-07 WO claimed
EP-1730232-A4 FAST CURING FLUOROELASTOMERIC COMPOSITIONS, ADHESIVE FLUOROELASTOMERIC COMPOSITIONS AND METHODS FOR BONDING FLUOROELASTOMERIC COMPOSITIONS GREENE TWEED INC (US) 2008-05-21 EP claimed
US-20070027260-A1 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. (US) 2007-02-01 US claimed
US-20060287438-A1 Fast curing fluoroelastomeric compositions, adhesive fluoroelastomeric compositions and methods for bonding fluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. 2006-12-21 US claimed
EP-1730232-A2 FAST CURING FLUOROELASTOMERIC COMPOSITIONS, ADHESIVE FLUOROELASTOMERIC COMPOSITIONS AND METHODS FOR BONDING FLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2006-12-13 EP claimed
EP-1587784-A2 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2005-10-26 EP claimed
WO-2005097890-A2 FAST CURING FLUOROELASTOMERIC COMPOSITIONS, ADHESIVE FLUOROELASTOMERIC COMPOSITIONS AND METHODS FOR BONDING FLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2005-10-20 WO claimed
US-20040214956-A1 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. 2004-10-28 US claimed
WO-2004069900-A2 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2004-08-19 WO claimed