SCHEMBL322433

SCHEMBL322433

N=C(N)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=N)N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2876518 1.00 THRB (0.33) THRB
SCHEMBL6255566 0.97 ALDH1A1 (0.30)
SCHEMBL4420537 0.91 THRB (0.46) THRB
SCHEMBL1009016 0.91 THRB (0.46) THRB
SCHEMBL11005732 0.89
SCHEMBL6577261 0.87
SCHEMBL1009774 0.84 THRB (0.32) THRB
SCHEMBL11000094 0.81
SCHEMBL1556023 0.76 ALDH1A1 (0.30)
SCHEMBL233273 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1587784-A4 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE TWEED INC (US) 2008-10-29 EP claimed
EP-1587784-A2 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2005-10-26 EP claimed
US-20040214956-A1 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. 2004-10-28 US claimed
WO-2004069900-A2 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2004-08-19 WO claimed
EP-2694571-B1 FLUOROPOLYETHER ELASTOMER COMPOSITIONS HAVING LOW GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES CO (US) 2018-12-26 EP disclosed
US-10023736-B2 Hybrid fluoroelastomer composition, curable composition, and methods of making and using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-07-17 US disclosed
US-9902836-B2 Fluoropolyether elastomer compositions having low glass transition temperatures 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-02-27 US disclosed
EP-2486080-B1 TRIAZINE CONTAINING FLUOROPOLYETHER ELASTOMERS HAVING VERY LOW GLASS TRANSITION TERMPERATURES, COMPOSITIONS CONTAINING THEM AND METHODS OF MAKING THEM 3M INNOVATIVE PROPERTIES CO (US) 2018-01-03 EP disclosed
US-9718961-B2 Fluoropolyether-polysiloxane elastomer compositions and shaped articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-08-01 US disclosed
EP-3013887-B1 FLUOROPOLYETHER-POLYSILOXANE ELASTOMER COMPOSITIONS AND SHAPED ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2017-07-26 EP disclosed
US-20170044367-A1 HYBRID FLUOROELASTOMER COMPOSITION, CURABLE COMPOSITION, AND METHODS OF MAKING AND USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-02-16 US disclosed
EP-3107950-A1 HYBRID FLUOROELASTOMER COMPOSITION, CURABLE COMPOSITION, AND METHODS OF MAKING AND USING THE SAME 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
US-20060287438-A1 Fast curing fluoroelastomeric compositions, adhesive fluoroelastomeric compositions and methods for bonding fluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. 2006-12-21 US disclosed
EP-1730232-A2 FAST CURING FLUOROELASTOMERIC COMPOSITIONS, ADHESIVE FLUOROELASTOMERIC COMPOSITIONS AND METHODS FOR BONDING FLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2006-12-13 EP disclosed
EP-1587784-A2 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2005-10-26 EP disclosed
WO-2005097890-A2 FAST CURING FLUOROELASTOMERIC COMPOSITIONS, ADHESIVE FLUOROELASTOMERIC COMPOSITIONS AND METHODS FOR BONDING FLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2005-10-20 WO disclosed
US-20050020859-A1 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. (US) 2005-01-27 US disclosed
WO-2005000917-A1 BISAMINOPEHNYL-BASED CURATIVES CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS. GREENE, TWEED OF DELAWARE, INC. (US) 2005-01-06 WO disclosed
US-20040214956-A1 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions GREENE, TWEED OF DELAWARE, INC. 2004-10-28 US disclosed
WO-2004069900-A2 BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2004-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020859-A1 Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions PFAS, FPGS, ALKBH2 THRB 4036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.