Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009016 | 1.00 | THRB (0.46) | THRBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL322433 | 0.91 | THRB (0.33) | THRB | |
| SCHEMBL2876518 | 0.91 | THRB (0.33) | THRB | |
| SCHEMBL1009774 | 0.88 | THRB (0.32) | THRBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6255566 | 0.88 | ALDH1A1 (0.30) | — | |
| SCHEMBL11005732 | 0.81 | — | — | |
| SCHEMBL6577261 | 0.79 | — | — | |
| SCHEMBL1556023 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL11000094 | 0.74 | — | — | |
| SCHEMBL4593915 | 0.72 | THRB (0.59) | THRBF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247749-B2 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | GREENE, TWEED OF DELAWARE, INC. (US) | 2007-07-24 | — | — | US | claimed |
| US-20050020859-A1 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | GREENE, TWEED OF DELAWARE, INC. (US) | 2005-01-27 | — | — | US | claimed |
| WO-2005000917-A1 | BISAMINOPEHNYL-BASED CURATIVES CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS. | GREENE, TWEED OF DELAWARE, INC. (US) | 2005-01-06 | — | — | WO | claimed |
| EP-1587784-B1 | BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS | GREENE TWEED INC (US) | 2014-10-15 | — | — | EP | disclosed |
| US-8362167-B2 | Fluorinated imidoylamidine vulcanizing agents for curing perfluoroelastomers polymers | LODESTAR INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362167-B2 | Fluorinated imidoylamidine vulcanizing agents for curing perfluoroelastomers polymers | LODESTAR INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-7521510-B2 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | GREENE, TWEED OF DELAWARE, INC (US) | 2009-04-21 | — | — | US | disclosed |
| EP-1587784-A4 | BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS | GREENE TWEED INC (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20080035883-A1 | Fluorinated imidoylamidines vulcanizing agents | LODESTAR, INC. | 2008-02-14 | — | — | US | disclosed |
| US-20080035883-A1 | Fluorinated imidoylamidines vulcanizing agents | LODESTAR, INC. | 2008-02-14 | — | — | US | disclosed |
| WO-2008008316-A2 | FLUORINATED IMIDOYLAMIDINES VULCANIZING AGENTS | LODESTAR INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| US-20070027260-A1 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | GREENE, TWEED OF DELAWARE, INC. (US) | 2007-02-01 | — | — | US | disclosed |
| EP-1587784-A2 | BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS | GREENE, TWEED OF DELAWARE, INC. (US) | 2005-10-26 | — | — | EP | disclosed |
| US-20050020859-A1 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | GREENE, TWEED OF DELAWARE, INC. (US) | 2005-01-27 | — | — | US | disclosed |
| WO-2005000917-A1 | BISAMINOPEHNYL-BASED CURATIVES CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS. | GREENE, TWEED OF DELAWARE, INC. (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040214956-A1 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | GREENE, TWEED OF DELAWARE, INC. | 2004-10-28 | — | — | US | disclosed |
| WO-2004069900-A2 | BISAMINOPHENYL-BASED CURATIVES AND AMIDINE-BASED CURATIVES AND CURE ACCELERATORS FOR PERFLUOROELASTOMERIC COMPOSITIONS | GREENE, TWEED OF DELAWARE, INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| US-4559175-A | THIO AND AZIDO DERIVATIVES; CORROSION AND OXIDATION RESISTANT ADDITIVES FOR FLUORO LUBRICANTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1985-12-17 | — | — | US | disclosed |
| US-4215072-A | Diphospha-s-triazines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1980-07-29 | — | — | US | disclosed |
| US-4194983-A | DIPHOSPHA-S-TRIAZINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1980-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080035883-A1 | Fluorinated imidoylamidines vulcanizing agents | AFF1, AFF2, AFF4 | THRB 2288/4885F2 58/4885PRSS1 4084/4885 |
| US-20050020859-A1 | Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions | PFAS, FPGS, ALKBH2 | THRB 4036/4885F2 1140/4885PRSS1 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.