Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379547 | 0.82 | KDM4E (0.41) | ALDH1A1HSD17B10SRCMAPTLMNA | |
| SCHEMBL379494 | 0.81 | SRC (0.47) | ALDH1A1HPGDSRCMEN1MAPT | |
| SCHEMBL6976544 | 0.79 | MEN1 (0.53) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1009369 | 0.76 | PLAU (0.49) | ALDH1A1HPGDCYP3A4HSD17B10MEN1 | |
| SCHEMBL1010818 | 0.76 | TRPV1 (0.40) | ALDH1A1HPGDSRCMEN1KMT2A | |
| SCHEMBL1010061 | 0.72 | HPGD (0.39) | ALDH1A1HPGDHSD17B10MEN1MAPT | |
| SCHEMBL29688279 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP3A4HSD17B10MAPK9 | |
| SCHEMBL1923372 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP3A4HSD17B10MAPK9 | |
| SCHEMBL28028253 | 0.71 | SRC (0.45) | ALDH1A1HPGDSRCMEN1MAPT | |
| SCHEMBL4171779 | 0.69 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP3A4HSD17B10MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801189-B1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE CO (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-1801189-B1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE CO (US) | 2012-11-07 | — | — | EP | disclosed |
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | disclosed |
| US-7501386-B2 | Lubricants for automotive and truck crankcase lubricants; as well as transmission lubricants, gear lubricants, hydraulic fluids, compressor oils, diesel and marine lubricants; superior oxidation inhibition; Phenyl-(1,2,3,4-tetrahydro-quinolin-6-yl)-amine, diphenylamine | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501386-B2 | Lubricants for automotive and truck crankcase lubricants; as well as transmission lubricants, gear lubricants, hydraulic fluids, compressor oils, diesel and marine lubricants; superior oxidation inhibition; Phenyl-(1,2,3,4-tetrahydro-quinolin-6-yl)-amine, diphenylamine | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501386-B2 | Lubricants for automotive and truck crankcase lubricants; as well as transmission lubricants, gear lubricants, hydraulic fluids, compressor oils, diesel and marine lubricants; superior oxidation inhibition; Phenyl-(1,2,3,4-tetrahydro-quinolin-6-yl)-amine, diphenylamine | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | disclosed |
| EP-1801104-A2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801104-A2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801189-A2 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801189-A2 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| US-20070142243-A1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142243-A1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142243-A1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | AHR, ARNT, HRH2 | ALDH1A1 242/4885HPGD 47/4885CYP3A4 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.