SCHEMBL379547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1009675	0.82	ALDH1A1 (0.41)	MAPTALDH1A1LMNAHSD17B10SRC
	SCHEMBL379494	0.82	SRC (0.47)	KDM4EMAPTALDH1A1HTTTDP1
	SCHEMBL1009709	0.78	MAPT (0.50)	KDM4EMAPTCA12CA1CA2
	SCHEMBL1010818	0.77	TRPV1 (0.40)	GAAALDH1A1LMNAHTTSRC
	SCHEMBL1009369	0.74	PLAU (0.49)	KDM4EMAPTCA12CA1CA2
	SCHEMBL1010061	0.73	HPGD (0.39)	MAPTGAAALDH1A1LMNATP53
	SCHEMBL4433435	0.72	MAPT (0.50)	KDM4EMAPTCA12CA1CA2
	SCHEMBL28028253	0.72	SRC (0.45)	KDM4EMAPTALDH1A1LMNATHRB
	SCHEMBL24429192	0.69	SRC (0.46)	KDM4EMAPTGAAALDH1A1HTT
	SCHEMBL28152072	0.69	MAPT (0.50)	KDM4EMAPTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.