Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984823 | 0.85 | HTR6 (0.48) | MEN1KMT2AGLO1TDP1PKM | |
| SCHEMBL6983864 | 0.82 | SLC40A1 (0.50) | TDP1PKMLMNAHTTALDH1A1 | |
| SCHEMBL6974140 | 0.82 | WDR5 (0.45) | LMNAHTTPTGES2ALDH1A1HTR2C | |
| SCHEMBL6982220 | 0.81 | ALDH1A1 (0.64) | LMNAHTTALDH1A1HTR2CHTR2B | |
| SCHEMBL6986762 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AGLO1PKMLMNA | |
| SCHEMBL6985112 | 0.81 | ALDH1A1 (0.64) | MEN1KMT2ATDP1PKMLMNA | |
| SCHEMBL6985321 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL6983098 | 0.80 | HCRTR1 (0.43) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL1009675 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10239990 | 0.76 | MEN1 (0.50) | MEN1KMT2AGLO1TDP1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |