SCHEMBL10098407

SCHEMBL10098407

Cc1ccc(Cc2ccc([SiH](C)C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.47
IDO1 P14902 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
ACHE P22303 1/20 0.38
AGXT P21549 2/20 0.38
LTA4H P09960 1/20 0.38
ALDH1A1 P00352 3/20 0.36
DAO P14920 1/20 0.36
HTT P42858 1/20 0.36
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16372648 0.90 ALDH1A1 (0.42) SRD5A2TDP1LTA4HALDH1A1HTT
SCHEMBL476102 0.84 ACHE (0.53) IDO1CYP2A6TDP1ACHEALDH1A1
SCHEMBL11410252 0.82 IDO1 (0.58) SRD5A2IDO1CYP1A2CYP2A6TAAR1
SCHEMBL1149394 0.82 IDO1 (0.58) SRD5A2IDO1CYP1A2CYP2A6TAAR1
SCHEMBL31216311 0.81 CALM1 (0.57) SRD5A2CYP1A2TAAR1LTA4HHTT
SCHEMBL10098397 0.77 ACHE (0.44) TDP1ACHEALDH1A1
SCHEMBL25449537 0.74 LTA4H (0.52) SRD5A2IDO1CYP1A2CYP2A6TAAR1
SCHEMBL1741096 0.74 LTA4H (0.52) SRD5A2IDO1CYP1A2CYP2A6TAAR1
SCHEMBL8385547 0.73 ACHE (0.53) IDO1CYP2A6TDP1ACHEALDH1A1
SCHEMBL28534675 0.73 MAPT (0.45) SRD5A2IDO1CYP1A2CYP2A6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207442-B2 Reinforcing structures for thin-film photovoltaic device substrates, and associated methods ITN ENERGY SYSTEMS, INC. (US) 2012-06-26 US disclosed