SCHEMBL1009863

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL379048	0.82	PRKCI (0.50)	NPC1RAB9AADRA2AADRA2BADRA2C
	SCHEMBL1009710	0.75	MAPT (0.52)	KMT2ANPC1RAB9AMEN1PKLR
	SCHEMBL7664793	0.74	ADRA2A (0.58)	KMT2ANPC1RAB9AADRA2AADRA2B
	SCHEMBL3801450	0.74	TAS1R3 (0.45)	KMT2ANPC1RAB9ACA12CA1
	SCHEMBL12188083	0.72	EGFR (0.39)	KMT2ARAB9AEGFRMEN1TAS1R3
	SCHEMBL2842912	0.72	HDAC3 (0.73)	KMT2ANPC1RAB9AMEN1TAS1R3
	SCHEMBL317647	0.72	PKLR (0.48)	NPC1RAB9ACA12CA1CA2
	SCHEMBL10280248	0.72	PRKCI (0.47)	NPC1RAB9ACA12CA1CA2
	SCHEMBL11821584	0.71	PLK1 (0.51)	NPC1RAB9ACA12CA1CA2
	Hydrochloric Acid SCHEMBL507190	0.71	PKLR (0.47)	NPC1RAB9ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.