Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280248 | 0.88 | PRKCI (0.47) | PRKCIPKMMAPTCA12CA1 | |
| SCHEMBL1009710 | 0.85 | MAPT (0.52) | PKMMAPTPKLRPLK1RAB9A | |
| SCHEMBL11724375 | 0.84 | PRKCI (0.51) | PRKCIPKMMAPTCA12CA1 | |
| SCHEMBL317647 | 0.84 | PKLR (0.48) | PRKCIPKMMAPTCA12CA1 | |
| SCHEMBL24783493 | 0.84 | PRKCI (0.47) | PRKCIPKMMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL31105738 | 0.82 | CA12 (0.50) | PRKCIPKMMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL507190 | 0.82 | PKLR (0.47) | PRKCIPKMMAPTCA12CA1 | |
| SCHEMBL1009863 | 0.82 | KMT2A (0.44) | PRKCIPKMMAPTCA12CA1 | |
| SCHEMBL11816447 | 0.80 | PKLR (0.45) | PRKCIPKMMAPTCA12CA1 | |
| SCHEMBL3801450 | 0.80 | TAS1R3 (0.45) | PRKCIPKMMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801105-B1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2012-01-25 | — | — | EP | claimed |
| US-7285518-B2 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2007-10-23 | — | — | US | claimed |
| EP-1801105-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | claimed |
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | claimed |
| EP-1801105-B1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-1801105-B1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2012-01-25 | — | — | EP | disclosed |
| US-7285518-B2 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2007-10-23 | — | — | US | disclosed |
| US-7285518-B2 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2007-10-23 | — | — | US | disclosed |
| US-7285518-B2 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2007-10-23 | — | — | US | disclosed |
| EP-1801105-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801105-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | ALOX12, ALOX15B, HRH1 | PRKCI 3335/4885PKM 4470/4885MAPT 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.