SCHEMBL10098933

SCHEMBL10098933

CNC(=O)C1CCC2C(=O)N(c3ccc(-c4ccc(C)cc4)cc3)C(=O)C2C1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.51
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.42
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 5/20 0.40
PKM P14618 1/20 0.40
POLB P06746 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10098936 0.91 LMNA (0.52) LMNATSHRMAPK1KMT2ARAB9A
SCHEMBL10098944 0.85 LMNA (0.49) LMNATSHRKMT2ARAB9AALDH1A1
SCHEMBL10098937 0.83 SMN1; SMN2 (0.52) LMNAKMT2ARAB9AALDH1A1PKM
SCHEMBL10098942 0.77 TP53 (0.40) TSHRKMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL10098938 0.76 ALDH1A1 (0.46) LMNAKMT2ARAB9AALDH1A1POLB
SCHEMBL10098932 0.74 CHRNB2 (0.36) LMNATSHRMAPK1ALDH1A1SMN1; SMN2
SCHEMBL12221373 0.73 LMNA (0.51) LMNAKMT2AALDH1A1POLBSMN1; SMN2
SCHEMBL1218625 0.73 POLB (0.64) LMNAMAPK1KMT2ARAB9AALDH1A1
SCHEMBL12221387 0.71 LMNA (0.47) LMNAKMT2ARAB9AALDH1A1PKM
SCHEMBL10098934 0.71 ALDH1A1 (0.49) LMNAKMT2ARAB9AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470913-B2 Thermosetting resin composition and cured product of the same DIC CORPORATION (JP) 2013-06-25 US disclosed
US-8222365-B2 Polyamideimide resin, as well as a colorless and transparent flexible metal-clad laminate and circuit board obtained therefrom TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-07-17 US disclosed
US-20120142829-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT OF THE SAME DIC CORPORATION (JP) 2012-06-07 US disclosed
US-20100018756-A1 POLYAMIDEIMIDE RESIN, AS WELL AS A COLORLESS AND TRANSPARENT FLEXIBLE METAL-CLAD LAMINATE AND CIRCUIT BOARD OBTAINED THEREFROM TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed