SCHEMBL10098937

SCHEMBL10098937

CCc1ccc(N2C(=O)C3CCC(C(=O)NC)CC3C2=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
LMNA P02545 2/20 0.48
RAB9A P51151 1/20 0.48
ALDH1A1 P00352 5/20 0.45
PKM P14618 1/20 0.45
NPSR1 Q6W5P4 2/20 0.43
POLB P06746 3/20 0.42
ACHE P22303 1/20 0.41
MGLL Q99685 1/20 0.39
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 3/20 0.38
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10098936 0.88 LMNA (0.52) SMN1; SMN2LMNARAB9AALDH1A1PKM
SCHEMBL10098944 0.85 LMNA (0.49) SMN1; SMN2LMNARAB9AALDH1A1PKM
SCHEMBL10098933 0.83 LMNA (0.51) SMN1; SMN2LMNARAB9AALDH1A1PKM
SCHEMBL10098932 0.74 CHRNB2 (0.36) SMN1; SMN2LMNAALDH1A1
SCHEMBL24862227 0.73 SMN1; SMN2 (0.54) SMN1; SMN2LMNARAB9AALDH1A1NPSR1
SCHEMBL22854275 0.72 RORC (0.53) SMN1; SMN2ALDH1A1NPSR1POLBMAPT
SCHEMBL10098942 0.70 TP53 (0.40) SMN1; SMN2ALDH1A1NPSR1MAPTKMT2A
SCHEMBL4490863 0.68 SYK (0.48) ALDH1A1POLBMAPTKMT2ATP53
SCHEMBL18965716 0.68 TSHR (0.30)
SCHEMBL3190638 0.66 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1NPSR1POLBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470913-B2 Thermosetting resin composition and cured product of the same DIC CORPORATION (JP) 2013-06-25 US disclosed
US-20120142829-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT OF THE SAME DIC CORPORATION (JP) 2012-06-07 US disclosed