SCHEMBL10098932

SCHEMBL10098932

CNC(=O)C1CCC2C(=O)N(C)C(=O)C2C1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
BCHE P06276 1/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19263933 0.81 ACHE (0.30) LMNAALDH1A1
SCHEMBL26590835 0.80 BRD4 (0.44) CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3
SCHEMBL10098944 0.78 LMNA (0.49) LMNATSHRALDH1A1SMN1; SMN2
SCHEMBL10098934 0.77 ALDH1A1 (0.49) LMNAALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL10098935 0.74 LMNA (0.56) LMNAALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL10098937 0.74 SMN1; SMN2 (0.52) LMNAALDH1A1SMN1; SMN2
SCHEMBL10098933 0.74 LMNA (0.51) LMNATSHRMAPK1ALDH1A1SMN1; SMN2
SCHEMBL19423931 0.74
SCHEMBL10098938 0.74 ALDH1A1 (0.46) LMNAALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL21423317 0.73 GAA (0.34) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2540759-B1 Thermosetting resin composition and cured product of the same DAINIPPON INK & CHEMICALS (JP) 2014-08-06 EP disclosed
EP-2436734-B1 THERMOSETTING RESIN COMPOSITE AND CURED PRODUCT THEREOF DAINIPPON INK & CHEMICALS (JP) 2014-07-23 EP disclosed
US-8470913-B2 Thermosetting resin composition and cured product of the same DIC CORPORATION (JP) 2013-06-25 US disclosed
US-8470913-B2 Thermosetting resin composition and cured product of the same DIC CORPORATION (JP) 2013-06-25 US disclosed
EP-2540759-A2 Thermosetting resin composition and cured product of the same DIC Corporation (JP) 2013-01-02 EP disclosed
US-8222365-B2 Polyamideimide resin, as well as a colorless and transparent flexible metal-clad laminate and circuit board obtained therefrom TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-07-17 US disclosed
US-8222365-B2 Polyamideimide resin, as well as a colorless and transparent flexible metal-clad laminate and circuit board obtained therefrom TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-07-17 US disclosed
US-20120142829-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT OF THE SAME DIC CORPORATION (JP) 2012-06-07 US disclosed
US-20120142829-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT OF THE SAME DIC CORPORATION (JP) 2012-06-07 US disclosed
US-20100018756-A1 POLYAMIDEIMIDE RESIN, AS WELL AS A COLORLESS AND TRANSPARENT FLEXIBLE METAL-CLAD LAMINATE AND CIRCUIT BOARD OBTAINED THEREFROM TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed
US-20100018756-A1 POLYAMIDEIMIDE RESIN, AS WELL AS A COLORLESS AND TRANSPARENT FLEXIBLE METAL-CLAD LAMINATE AND CIRCUIT BOARD OBTAINED THEREFROM TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed