Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240941 | 0.80 | HSD17B10 (0.42) | HSD17B10SLC6A9TSHRKMT2A | |
| Tetraxetan SCHEMBL2017956 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL6848102 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL3503521 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| Tetraxetan SCHEMBL2635294 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL321989 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| Tetraxetan SCHEMBL18018 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL173508 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL6744121 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL3660521 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114832119-B | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2024-02-09 | — | — | CN | claimed |
| CN-114832119-A | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2022-08-02 | — | — | CN | claimed |
| CN-114832119-B | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2024-02-09 | — | — | CN | disclosed |
| US-20230109283-A1 | ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY | NANOH (FR) | 2023-04-06 | — | — | US | disclosed |
| CN-114832119-A | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2022-08-02 | — | — | CN | disclosed |
| US-10987435-B2 | Ultrafine nanoparticles comprising a functionalized polyorganosiloxane matrix and including metal complexes; method for obtaining same and uses thereof in medical imaging and/or therapy | INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (FR) | 2021-04-27 | — | — | US | disclosed |
| US-20210106677-A1 | VACCINE DEVELOPMENT METHODOLOGY BASED ON AN ADHESION MOLECULE | MATSFIDE, INC. (US) | 2021-04-15 | — | — | US | disclosed |
| US-20210000843-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2021-01-07 | — | — | US | disclosed |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| EP-3711781-A1 | METHOD FOR PREPARATION OF RADIOISOTOPE CHELATING POLYMER NANOPARTICLES FOR USE IN DIAGNOSTICS AND TREATMENT | Nanothea Spolka Akcyjna (PL) | 2020-09-23 | — | — | EP | disclosed |
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180008621-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-01-11 | — | — | US | disclosed |
| US-20180008729-A1 | ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY | THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FRENCH NATIONAL CENTRE FOR SCIENTIFIC RESEARCH) (FR) | 2018-01-11 | — | — | US | disclosed |
| EP-2268654-B1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | UNIV CALIFORNIA (US) | 2017-01-25 | — | — | EP | disclosed |
| US-20130195766-A1 | ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY | NANOH (FR) | 2013-08-01 | — | — | US | disclosed |
| US-20110144065-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | U.S. DEPARTMENT OF ENERGY | 2011-06-16 | — | — | US | disclosed |
| US-20110110866-A1 | Elastin-like polypeptide and gadolinium conjugate for magnetic resonance imaging | DUKE UNIVERSITY (US) | 2011-05-12 | — | — | US | disclosed |
| EP-2268654-A2 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | The Regents of the University of California (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2010065572-A1 | SSTR1-SELECTIVE ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009132020-A2 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | HSD17B10 3818/4885SLC6A9 3554/4885TSHR 754/4885 |
| US-20110110866-A1 | Elastin-like polypeptide and gadolinium conjugate for magnetic resonance imaging | ELANE, ENPEP, ERMP1 | HSD17B10 3951/4885SLC6A9 1837/4885TSHR 2847/4885 |
| US-20110144065-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | HSD17B10 3818/4885SLC6A9 3554/4885TSHR 754/4885 |
| US-10987435-B2 | Ultrafine nanoparticles comprising a functionalized polyorganosiloxane matrix and including metal complexes; method for obtaining same and uses thereof in medical imaging and/or therapy | MPI, RXFP1, SNRPA | HSD17B10 4137/4885SLC6A9 3635/4885TSHR 1453/4885 |
| US-20180008621-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | HSD17B10 3818/4885SLC6A9 3554/4885TSHR 754/4885 |
| US-20180008729-A1 | ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY | MPI, RXFP1, SNRPA | HSD17B10 4137/4885SLC6A9 3635/4885TSHR 1453/4885 |
| US-20130195766-A1 | ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY | PAICS, F12, MPI | HSD17B10 4343/4885SLC6A9 3740/4885TSHR 2264/4885 |
| US-20230109283-A1 | ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY | SNRPD1, MPI, PSMA1 | HSD17B10 3663/4885SLC6A9 4292/4885TSHR 1951/4885 |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | HSD17B10 3818/4885SLC6A9 3554/4885TSHR 754/4885 |
| US-20210000843-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | HSD17B10 3818/4885SLC6A9 3554/4885TSHR 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.