Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871511 | 0.91 | LTA4H (0.70) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL8368668 | 0.86 | LSS (0.56) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL10457449 | 0.86 | APP (0.59) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL27472817 | 0.85 | KCNA3 (0.76) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL16089599 | 0.84 | TAAR1 (0.48) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL27962 | 0.83 | KCNA3 (0.82) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL18429633 | 0.83 | APP (0.68) | LTA4HHDAC6APP | |
| SCHEMBL5961821 | 0.82 | KCNH2 (0.50) | KCNA3TAAR1ALDH1A1RECQLDRD2 | |
| SCHEMBL19326851 | 0.81 | KCNH2 (0.46) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL10457904 | 0.81 | KDM4E (0.54) | ALDH1A1LTA4HPLA2G2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20220213095-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-07 | — | — | US | disclosed |
| US-11225478-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-01-18 | — | — | US | disclosed |
| US-20200325138-A1 | P2X7 Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-10-15 | — | — | US | disclosed |
| US-10703749-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-07-07 | — | — | US | disclosed |
| EP-3495365-A1 | P2X7 MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |
| US-20190092770-A1 | P2X7 Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2019-03-28 | — | — | US | disclosed |
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | disclosed |
| EP-3239151-A1 | P2X7 MODULATORS | Janssen Pharmaceutica NV (BE) | 2017-11-01 | — | — | EP | disclosed |
| EP-2013179-A1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2009-01-14 | — | — | EP | disclosed |
| US-20080153005-A1 | Non-Aqueous Electrolyte and Non-Aqueous Electrolyte Battery Comprising the Same | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
| WO-2007118859-A1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1798792-A1 | NONAQUEOUS ELECTROLYTE SOLUTION, AND NONAQUEOUS ELECTROLYTE BATTERY HAVING SAME | Bridgestone Corporation (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-20030229113-A1 | Keratinocyte growth inhibitors and hydroxamic acid derivatives | AKZO NOBEL N.V. (NL) | 2003-12-11 | — | — | US | disclosed |
| EP-0357409-B1 | Heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 1994-07-20 | — | — | EP | disclosed |
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0357409-A2 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4883789-A | Substituted phenyltrialkylsilane insecticides | FMC CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| US-4801717-A | PLANT GROWTH REGULATORS | ROUSSEL UCLAF (FR) | 1989-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325138-A1 | P2X7 Modulators | P2RX2, P2RX7, P2RY2 | KCNA3 230/4885TAAR1 894/4885ALDH1A1 1628/4885 |
| US-20030229113-A1 | Keratinocyte growth inhibitors and hydroxamic acid derivatives | FGF1, FGF2, EGFR | KCNA3 2951/4885TAAR1 4113/4885ALDH1A1 2165/4885 |
| US-20190092770-A1 | P2X7 Modulators | P2RX2, P2RX7, P2RY2 | KCNA3 230/4885TAAR1 894/4885ALDH1A1 1628/4885 |
| US-11225478-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | KCNA3 230/4885TAAR1 894/4885ALDH1A1 1628/4885 |
| US-11820770-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | KCNA3 230/4885TAAR1 894/4885ALDH1A1 1628/4885 |
| US-20220213095-A1 | P2X7 MODULATORS | P2RX2, P2RX7, P2RY2 | KCNA3 230/4885TAAR1 894/4885ALDH1A1 1628/4885 |
| US-10703749-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | KCNA3 230/4885TAAR1 894/4885ALDH1A1 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.