Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961821 | 0.88 | KCNH2 (0.50) | ALDH1A1SMN1; SMN2TSHRKCNH2MAPK1 | |
| SCHEMBL9871511 | 0.86 | LTA4H (0.70) | LTA4HPLA2G2AALDH1A1TSHRKCNH2 | |
| SCHEMBL11705181 | 0.83 | KDM4E (0.59) | KDM4ELTA4HALDH1A1TDP1LMNA | |
| SCHEMBL13886635 | 0.83 | LTA4H (0.61) | KDM4ELTA4HPLA2G2AALDH1A1TDP1 | |
| SCHEMBL1009986 | 0.81 | KCNA3 (0.67) | LTA4HPLA2G2AALDH1A1KCNH2 | |
| SCHEMBL6054900 | 0.81 | LTA4H (0.63) | KDM4ELTA4HALDH1A1TDP1LMNA | |
| SCHEMBL9869869 | 0.80 | FFAR1 (0.53) | LTA4HPLA2G2AFFAR1FFAR4MAOB | |
| SCHEMBL14280088 | 0.79 | LTA4H (0.55) | KDM4ELTA4HALDH1A1TDP1LMNA | |
| SCHEMBL24648592 | 0.79 | KDM4E (0.56) | KDM4ELTA4HPLA2G2AALDH1A1TDP1 | |
| SCHEMBL8778562 | 0.79 | KDM4E (0.56) | KDM4ELTA4HPLA2G2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |