Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10100471 | 0.85 | CTSK (0.58) | CTSLCTSSCTSK | |
| SCHEMBL17279329 | 0.84 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL11308449 | 0.84 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL17694104 | 0.84 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL19519898 | 0.83 | CTSL (0.59) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL4787188 | 0.83 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL1199556 | 0.83 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL21357647 | 0.83 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL7689520 | 0.83 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL2963543 | 0.83 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097750-B2 | Highly enantioselective, converting aromatic and aliphatic aldehydes into optically active aryl and alkyl beta -amino acids | BRANDEIS UNIVERSITY (US) | 2012-01-17 | — | — | US | disclosed |
| US-20080228000-A1 | Cinchona Alkaloid-Catalyzed Asymmetric Mannich Reactions | BRANDEIS UNIVERSITY (US) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080228000-A1 | Cinchona Alkaloid-Catalyzed Asymmetric Mannich Reactions | MANBA, MAN2A1, ASNS | CTSL 1323/4885CTSS 104/4885SIRT2 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.