Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077746 | 0.84 | P2RX3 (0.37) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL19650317 | 0.84 | GAA (0.44) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL23288682 | 0.79 | THRB (0.37) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL5166833 | 0.79 | P2RX3 (0.45) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL15927601 | 0.78 | P2RX3 (0.41) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL13059718 | 0.77 | GAA (0.48) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL12190518 | 0.77 | P2RX3 (0.48) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL22781546 | 0.77 | TUBB1 (0.34) | LMNAMAPK1HTTRAB9A | |
| SCHEMBL24449860 | 0.77 | ALOX15 (0.40) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL18387027 | 0.76 | CETP (0.31) | P2RX3P2RX2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468735-A1 | Synthesis of intermediates for preparing anacetrapib and derivates thereof | LEK Pharmaceuticals d.d. (SI) | 2012-06-27 | — | — | EP | disclosed |