Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104459 | 0.94 | MAPT (0.33) | ADRA2AADRA2BADRA2CCA12CA2 | |
| SCHEMBL12531421 | 0.94 | MAPT (0.33) | ADRA2AADRA2BADRA2CCA12CA2 | |
| SCHEMBL16070320 | 0.90 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CCA12CA2 | |
| SCHEMBL10104454 | 0.88 | ADRA2A (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL13924741 | 0.86 | PABPC1 (0.36) | — | |
| SCHEMBL12861149 | 0.84 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CCA12CA2 | |
| SCHEMBL10104003 | 0.81 | — | — | |
| SCHEMBL10104456 | 0.79 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CCA12CA2 | |
| SCHEMBL10104005 | 0.76 | MAPT (0.44) | MAPT | |
| SCHEMBL16070309 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| EP-2336248-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-22 | — | — | EP | disclosed |
| EP-2333018-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330160-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-08 | — | — | EP | disclosed |
| EP-1647580-B1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. | OREAL (FR) | 2011-02-16 | — | — | EP | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| US-7488354-B2 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2009-02-10 | — | — | US | disclosed |
| EP-2018847-A1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | ADRA2A 4212/4885ADRA2B 4146/4885ADRA2C 4216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.