Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104454 | 0.93 | ADRA2A (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL12531421 | 0.84 | MAPT (0.33) | ADRA2AADRA2BADRA2CMAPTCA12 | |
| SCHEMBL10104459 | 0.84 | MAPT (0.33) | ADRA2AADRA2BADRA2CMAPTCA12 | |
| SCHEMBL18774205 | 0.81 | — | — | |
| SCHEMBL10104464 | 0.79 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CMAPTCA12 | |
| SCHEMBL10104068 | 0.79 | KDM4A (0.38) | MAPT | |
| SCHEMBL16070320 | 0.78 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CCA12CA2 | |
| SCHEMBL13924741 | 0.77 | PABPC1 (0.36) | — | |
| SCHEMBL12861149 | 0.77 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CMAPTCA12 | |
| SCHEMBL10104002 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345652-B2 | Composition for dyeing keratin fibres comprising a direct dye bearing a disulphide/thiol function, a sparingly or non-ethoxylated fatty alcohol, a cationic surfactant, an alkaline agent and a reducing agent | L'OREAL (FR) | 2016-05-24 | — | — | US | disclosed |
| US-9271915-B2 | Composition for dyeing keratin fibres comprising a direct dye bearing a disulphide/thiol function, a non-cellulose-based thickening polymer, an alkaline agent and a reducing agent | L'OREAL (FR) | 2016-03-01 | — | — | US | disclosed |
| US-8840684-B2 | Process for dyeing keratin fibres using a direct dye bearing a disulfide/thiol/protected thiol function and water vapour | L'OREAL (FR) | 2014-09-23 | — | — | US | disclosed |
| US-20140041132-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULPHIDE/THIOL FUNCTION, A NON-CELLULOSE-BASED THICKENING POLYMER, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2014-02-13 | — | — | US | disclosed |
| US-20130283544-A1 | PROCESS FOR DYEING KERATIN FIBRES USING A DIRECT DYE BEARING A DISULFIDE/THIOL/PROTECTED THIOL FUNCTION AND WATER VAPOUR | L'OREAL (FR) | 2013-10-31 | — | — | US | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| EP-2336248-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-22 | — | — | EP | disclosed |
| EP-2333018-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330160-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-08 | — | — | EP | disclosed |
| EP-1647580-B1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. | OREAL (FR) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009109457-A2 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE DIRECT DYE COMPRISING A DISULPHIDE/PROTECTED-THIOL FUNCTION AND AT LEAST ONE SILICEOUS COMPOUND COMPRISING A THIOL FUNCTION AND METHOD USING THE COMPOSITION | L'OREAL (FR) | 2009-09-11 | — | — | WO | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| EP-2053094-A2 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | L'Oréal (FR) | 2009-04-29 | — | — | EP | disclosed |
| US-7488354-B2 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2009-02-10 | — | — | US | disclosed |
| EP-2018847-A1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130283544-A1 | PROCESS FOR DYEING KERATIN FIBRES USING A DIRECT DYE BEARING A DISULFIDE/THIOL/PROTECTED THIOL FUNCTION AND WATER VAPOUR | KRT18, TST, PDIA5 | ADRA2A 3905/4885ADRA2B 3578/4885ADRA2C 3975/4885 |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | ADRA2A 4212/4885ADRA2B 4146/4885ADRA2C 4216/4885 |
| US-20140041132-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULPHIDE/THIOL FUNCTION, A NON-CELLULOSE-BASED THICKENING POLYMER, AN ALKALINE AGENT AND A REDUCING AGENT | KRT18, DSG1, KLK5 | ADRA2A 4484/4885ADRA2B 4228/4885ADRA2C 4121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.