Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078286 | 0.72 | SIGMAR1 (0.48) | MC4RSIGMAR1ELANEF2PLG | |
| SCHEMBL29272014 | 0.67 | MC4R (0.41) | MC4RSIGMAR1ELANEF2PLG | |
| SCHEMBL23131277 | 0.65 | GSK3A (0.34) | LMNAGSK3AGSK3B | |
| SCHEMBL28659205 | 0.64 | SIGMAR1 (0.50) | MC4RSIGMAR1ELANEF2PLG | |
| SCHEMBL4084451 | 0.64 | LMNA (0.45) | MC4RSIGMAR1ELANEF2PLG | |
| SCHEMBL24701942 | 0.64 | LMNA (0.39) | MC4RSIGMAR1ELANEF2PLG | |
| Hydrochloric Acid SCHEMBL29906145 | 0.64 | GSK3A (0.37) | SIGMAR1ELANEF2PLGCTSG | |
| SCHEMBL14812572 | 0.63 | ELANE (0.42) | MC4RSIGMAR1ELANEF2PLG | |
| SCHEMBL22172085 | 0.62 | ELANE (0.50) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL4308587 | 0.61 | LMNA (0.39) | MC4RSIGMAR1ELANEF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085475-A1 | NOVEL PLATINUM-CARBENE COMPLEXES AND USE THEREOF AS MEDICAMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085479-A1 | PROCESS FOR PREPARING PLATINUM-CARBENE COMPLEXES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-06-28 | — | — | WO | disclosed |