SCHEMBL4308587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24747035	0.74	LMNA (0.37)	LMNAPOLBSIGMAR1KDM4ENPSR1
	SCHEMBL14812572	0.71	ELANE (0.42)	LMNAPOLBSIGMAR1KDM4ENPSR1
	SCHEMBL4084451	0.69	LMNA (0.45)	LMNAPOLBSIGMAR1KDM4ENPSR1
	SCHEMBL1078286	0.68	SIGMAR1 (0.48)	LMNASIGMAR1KDM4EALDH1A1MEN1
	SCHEMBL28946773	0.64	POLB (0.50)	LMNAPOLBSIGMAR1NPSR1ALDH1A1
	SCHEMBL24701942	0.64	LMNA (0.39)	LMNAPOLBSIGMAR1KDM4ENPSR1
	SCHEMBL13801222	0.63	SIGMAR1 (0.60)	LMNAPOLBSIGMAR1ALDH1A1MC4R
	SCHEMBL4084447	0.63	LMNA (0.48)	LMNAPOLBSIGMAR1NPSR1ALDH1A1
	SCHEMBL5456203	0.61	EPHX2 (0.46)	LMNAPOLBSIGMAR1ALDH1A1MEN1
	SCHEMBL10105148	0.61	MC4R (0.40)	LMNAPOLBSIGMAR1TSHRF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.