Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084451 | 0.76 | LMNA (0.45) | LMNASMN1; SMN2TSHRPOLBSIGMAR1 | |
| SCHEMBL1078286 | 0.71 | SIGMAR1 (0.48) | LMNASMN1; SMN2SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL28300318 | 0.66 | NOTUM (0.40) | LMNASMN1; SMN2TSHRPOLBNOTUM | |
| SCHEMBL4084447 | 0.66 | LMNA (0.48) | LMNAPOLBNOTUMSIGMAR1NPSR1 | |
| SCHEMBL14812572 | 0.65 | ELANE (0.42) | LMNASMN1; SMN2TSHRPOLBSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4081730 | 0.64 | LMNA (0.47) | LMNAPOLBNOTUMSIGMAR1NPSR1 | |
| SCHEMBL4308587 | 0.64 | LMNA (0.39) | LMNASMN1; SMN2TSHRPOLBSIGMAR1 | |
| SCHEMBL10105148 | 0.64 | MC4R (0.40) | LMNASMN1; SMN2TSHRPOLBSIGMAR1 | |
| SCHEMBL28946773 | 0.63 | POLB (0.50) | LMNAPOLBSIGMAR1NPSR1ALDH1A1 | |
| SCHEMBL24747035 | 0.62 | LMNA (0.37) | LMNASMN1; SMN2TSHRPOLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4101843-A1 | METHOD FOR PRODUCING AROMATIC HETEROCYCLIC RING-SUBSTITUTED DIFLUOROACETIC ACID DERIVATIVE | AGC INC. (JP) | 2022-12-14 | — | — | EP | disclosed |
| EP-4101842-A1 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUND | AGC INC. (JP) | 2022-12-14 | — | — | EP | disclosed |