Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162352 | 0.87 | TDP1 (0.56) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL7403879 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25167821 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL9430839 | 0.83 | CYP1A2 (0.54) | ALDH1A1KMT2AKDM4EMAPTCYP1A2 | |
| SCHEMBL2390452 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL2091191 | 0.82 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL2512014 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL11536864 | 0.81 | CYP1A2 (0.73) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL16753842 | 0.81 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4392689 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165520-A1 | PROCESS FOR THE SYNTHESIS OF PRODRUGS OF OPIOIDS | SHIRE LLC | 2012-06-28 | — | — | US | disclosed |
| US-20110190267-A1 | PRODRUGS OF OPIOIDS AND USES THEREOF | SHIRE PHARMACEUTICALS, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190267-A1 | PRODRUGS OF OPIOIDS AND USES THEREOF | OPRK1, OPRL1, OPRM1 | ALDH1A1 225/4885TUBB4A 3344/4885TUBB 3965/4885 |
| US-20120165520-A1 | PROCESS FOR THE SYNTHESIS OF PRODRUGS OF OPIOIDS | OPRM1, OPRK1, OPRD1 | ALDH1A1 276/4885TUBB4A 1580/4885TUBB 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.