Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042674 | 0.79 | ALDH1A1 (0.58) | ALDH1A1IDO1MCL1TAAR1MAOB | |
| SCHEMBL31634194 | 0.76 | ALDH1A1 (0.54) | ALDH1A1IDO1MCL1TAAR1MAOB | |
| SCHEMBL13594319 | 0.76 | IDO1 (0.61) | ALDH1A1IDO1MCL1TAAR1MAOB | |
| SCHEMBL31065556 | 0.75 | IDO1 (0.67) | ALDH1A1IDO1MCL1TAAR1MAOB | |
| SCHEMBL2714973 | 0.75 | IDO1 (0.67) | ALDH1A1IDO1MCL1TAAR1MAOB | |
| SCHEMBL1681167 | 0.73 | ALDH1A1 (0.51) | ALDH1A1IDO1MCL1MAOBMEN1 | |
| SCHEMBL1520141 | 0.71 | IDO1 (1.00) | ALDH1A1IDO1TAAR1MAOB | |
| SCHEMBL540771 | 0.71 | LMNA (0.55) | ALDH1A1IDO1TAAR1MAOBMEN1 | |
| SCHEMBL13590064 | 0.71 | IDO1 (0.61) | ALDH1A1IDO1MCL1TAAR1MAOB | |
| SCHEMBL155804 | 0.71 | IDO1 (0.61) | ALDH1A1IDO1MCL1TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | THE UNIVERSITY OF MELBOURNE of ROYAL PARADE PARKVILLE (AU) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | PTGES2, PTGES, PTGES3 | ALDH1A1 2237/4885IDO1 2049/4885MCL1 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.