Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207532 | 0.76 | IP6K1 (0.46) | IP6K1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10108427 | 0.76 | MAOA (0.38) | IP6K1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7561946 | 0.73 | ALDH1A1 (0.52) | IP6K1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7561953 | 0.73 | ALDH1A1 (0.52) | IP6K1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4767226 | 0.67 | KDR (0.59) | IP6K1RAB9AKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10108322 | 0.65 | TAAR1 (0.44) | IP6K1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13264504 | 0.62 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RECQLKMT2AMEN1 | |
| SCHEMBL28198316 | 0.62 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RECQLKMT2AMEN1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28156521 | 0.61 | MAOB (0.65) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28291545 | 0.61 | MAOB (0.65) | ALDH1A1KMT2AMEN1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | NTRK3, TK1, TNNI3K | IP6K1 1320/4885RAB9A 3682/4885KDM4E 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.