Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102702 | 0.78 | LMNA (0.42) | MAOAMAOBCSNK2A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10108326 | 0.76 | IP6K1 (0.46) | ALDH1A1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL10108425 | 0.72 | CSNK2A1 (0.40) | CSNK2A1ALDH1A1KDM4ELMNAPDE4A | |
| SCHEMBL11067774 | 0.62 | TDP1 (0.70) | RAB9ASMN1; SMN2GAALMNATSHR | |
| SCHEMBL27280793 | 0.59 | SIGMAR1 (0.46) | MAOAMAOBRAB9A | |
| (Z)-1,2-Diphenylethene SCHEMBL6887771 | 0.59 | RELA (0.50) | MAOAMAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL6887768 | 0.59 | RELA (0.50) | MAOAMAOB | |
| SCHEMBL10108322 | 0.58 | TAAR1 (0.44) | ALDH1A1KDM4EHPGDGAALMNA | |
| (Z)-1,2-Diphenylethene SCHEMBL27660887 | 0.57 | MAOB (0.55) | MAOAMAOBALDH1A1SMN1; SMN2LMNA | |
| (Z)-1,2-Diphenylethene SCHEMBL28743228 | 0.57 | MAOB (0.69) | MAOAMAOBALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | NTRK3, TK1, TNNI3K | MAOA 1827/4885MAOB 855/4885CSNK2A1 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.