SCHEMBL10108499

SCHEMBL10108499

Cc1cc(C)c(N2CC(C)(C)CC2(C)C)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22279345 0.83
SCHEMBL25098480 0.75 SLC18A3 (0.33) ALDH1A1MAPTSMN1; SMN2
SCHEMBL16307943 0.71 ALDH1A1 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL22279346 0.70 ALDH1A1 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL22279348 0.70
Hydrochloric Acid SCHEMBL1903929 0.70 ALDH1A1 (0.35) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL813736 0.68 ALDH1A1 (0.39) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL22279344 0.67 SLC18A3 (0.37) MAPT
SCHEMBL388608 0.65 ALDH1A1 (0.36) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL388609 0.65 ALDH1A1 (0.36) ALDH1A1POLBMAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220179-A1 Processes for Producing Cyclic Olefins from Polymers and Re-Polymerization Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2023-07-13 US disclosed
WO-2021242636-A1 PROCESSES FOR PRODUCING CYCLIC OLEFINS FROM POLYMERS AND RE-POLYMERIZATION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-02 WO disclosed
US-9181360-B2 Polymers prepared by ring opening / cross metathesis EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-11-10 US disclosed
US-9169334-B2 Preparation of bottlebrush polymers via ring-opening metathesis polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-10-27 US disclosed
US-8809563-B2 Metathesis catalyst and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-08-19 US disclosed
US-20140213732-A1 Preparation of Bottlebrush Polymers via Ring-Opening Metathesis Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2014-07-31 US disclosed
US-8759469-B2 Synthesis of urethanes and polyurethanes catalysed by carbenes Vencorex Frence (FR) 2014-06-24 US disclosed
US-8524930-B2 Class of olefin metathesis catalysts, methods of preparation, and processes for the use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-03 US disclosed
US-8524930-B2 Class of olefin metathesis catalysts, methods of preparation, and processes for the use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-03 US disclosed
US-8519147-B2 Carbene complexes of lithium and/or magnesium metal salts, and uses thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-08-27 US disclosed
WO-2012040088-A2 A NOVEL CLASS OF OLEFIN METATHESIS CATALYSTS, METHODS OF PREPARATION, AND PROCESSES FOR THE USE THEREOF EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2012-03-29 WO disclosed
US-20120077945-A1 Novel Class Of Olefin Metathesis Catalysts, Methods Of Preparation, And Processes For The Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-03-29 US disclosed
WO-2011100022-A2 METATHESIS CATALYST AND PROCESS FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-18 WO disclosed
US-20110112304-A1 Carbene Complexes of Lithium And/Or Magnesium Metal Salts, And Uses Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2011-05-12 US disclosed
US-20110046301-A1 SYNTHESIS OF URETHANES AND POLYURETHANES CATALYSED BY CARBENES PERSTORP FRANCE (FR) 2011-02-24 US disclosed
US-20100113791-A1 PREPARATION OF PRECURSORS OF CARBENES OF CAAC TYPE AND PREPARING SAID CARBENES THEREFROM RHODIA OPERATIONS (FR) 2010-05-06 US disclosed
WO-2009016322-A2 SYNTHESIS OF URETHANES AND OF POLYURETHANES CATALYSED BY CARBENES RHODIA OPERATIONS (FR) 2009-02-05 WO disclosed
WO-2009013344-A1 OPENING OF EPOXY CYCLES BY CARBENES RHODIA OPERATIONS (FR) 2009-01-29 WO disclosed
WO-2008125568-A1 PROCESS FOR PREPARING PRECURSORS OF CARBENES OF CAAC TYPE AND USE THEREOF FOR PREPARING SAID CARBENES RHODIA OPERATIONS (FR) 2008-10-23 WO disclosed
WO-2008095785-A1 NOVEL MIXED ORGANOMETALLIC COMPLEXES BASED ON CARBENES COMPRISING AN ALKYL AMINOCYCLIC UNIT RHODIA OPERATIONS (FR) 2008-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220179-A1 Processes for Producing Cyclic Olefins from Polymers and Re-Polymerization Thereof COASY, PTGIS, PUF60 ALDH1A1 1418/4885POLB 512/4885MAPT 2039/4885
US-20100113791-A1 PREPARATION OF PRECURSORS OF CARBENES OF CAAC TYPE AND PREPARING SAID CARBENES THEREFROM CCNC, HCCS, CYCS ALDH1A1 2543/4885POLB 3559/4885MAPT 2250/4885
US-20110112304-A1 Carbene Complexes of Lithium And/Or Magnesium Metal Salts, And Uses Thereof MCOLN2, CCNT1, MCOLN1 ALDH1A1 4148/4885POLB 1713/4885MAPT 2851/4885
US-20120077945-A1 Novel Class Of Olefin Metathesis Catalysts, Methods Of Preparation, And Processes For The Use Thereof C1S, PYM1, AOX1 ALDH1A1 390/4885POLB 4144/4885MAPT 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.