SCHEMBL10109896

SCHEMBL10109896

CC1(C)c2cc(-c3ccccc3)ccc2-c2ccc(N(c3ccc(-c4cccc5c4oc4ccccc45)cc3)c3ccc4c(c3)C(C)(C)c3cc(-c5ccccc5)ccc3-4)cc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
GGPS1 O95749 1/20 0.36
PRKDC P78527 4/20 0.36
PTGES2 Q9H7Z7 1/20 0.34
CDC14B O60729 2/20 0.33
CDC14A Q9UNH5 2/20 0.33
PDK2 Q15119 1/20 0.33
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
TNKS O95271 1/20 0.31
AVPR1A P37288 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
ALK Q9UM73 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20466621 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916322 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916626 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916344 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916575 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916584 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL10110012 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916324 0.99 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916585 0.99 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916625 0.99 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2CDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10411192-B2 Aromatic amine compound, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-09-10 US disclosed
US-10276637-B2 Organic EL multi-color light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-30 US disclosed
US-20180226601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, DISPLAY DEVICE, AND MIXED MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2018-08-09 US disclosed
US-20180226601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, DISPLAY DEVICE, AND MIXED MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2018-08-09 US disclosed
US-9966539-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2018-05-08 US disclosed
US-9966539-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2018-05-08 US disclosed
US-9871203-B2 Aromatic amine derivative, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 US disclosed
US-9871203-B2 Aromatic amine derivative, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 US disclosed
US-20160181526-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed
US-20160181526-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed
US-20140061602-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20140061602-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20120242218-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120242218-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed
US-20100001636-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-01-07 US disclosed
US-20100001636-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE TYR, TERF2, SAT1 ALOX5 3505/4885GGPS1 2974/4885PRKDC 2266/4885
US-10411192-B2 Aromatic amine compound, organic electroluminescent element and electronic device AOC2, PNMT, TYR ALOX5 2629/4885GGPS1 4160/4885PRKDC 3008/4885
US-20160181526-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE AOC2, PNMT, TYR ALOX5 2629/4885GGPS1 4160/4885PRKDC 3008/4885
US-20100001636-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE TYR, TERF2, SAT1 ALOX5 3311/4885GGPS1 2901/4885PRKDC 2270/4885
US-20180226601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, DISPLAY DEVICE, AND MIXED MATERIAL TMEM109, L1CAM, CD99 ALOX5 1998/4885GGPS1 2109/4885PRKDC 4289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.