SCHEMBL1011250

SCHEMBL1011250

Cc1ccc(N=C=N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTR3E A5X5Y0 2/20 0.41
HTR3B O95264 2/20 0.41
HTR3A P46098 2/20 0.41
HTR3D Q70Z44 2/20 0.41
HTR3C Q8WXA8 2/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
PLAU P00749 1/20 0.41
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MAPK1 P28482 2/20 0.35
STAT3 P40763 1/20 0.35
STAT1 P42224 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19876727 0.78 CYP3A4 (0.50) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL159755 0.78 ACHE (0.47) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL93286 0.74 CYP3A4 (0.56) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL11051784 0.74 CYP2A6 (0.42) SLC22A2SLC22A1SLC22A3PLAUCYP2C9
SCHEMBL10895667 0.74 HTR3E (0.46) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL8740945 0.74 ACHE (0.42) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL508504 0.74 S100B (0.44) NPC1RAB9AMAPTALDH1A1ESR2
SCHEMBL332260 0.74 MIF (0.56) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL9887642 0.74 ACHE (0.42) ACHETDP1HTR3EHTR3BHTR3A
SCHEMBL27614429 0.74 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289901-A2 THERMOFORMED ARTICLE Novamont S.p.A. (IT) 2023-12-13 EP claimed
EP-4032953-B1 THERMOFORMED ARTICLE NOVAMONT SPA (IT) 2023-12-06 EP claimed
US-11767425-B2 Polymer composition for the manufacture of thermoformed articles NOVAMONT S.P.A. (IT) 2023-09-26 US claimed
CN-115651371-A Polymer composition for making thermoformed articles 诺瓦蒙特股份公司 2023-01-31 CN claimed
CN-115556452-A Polymer composition for making thermoformed articles 诺瓦蒙特股份公司 2023-01-03 CN claimed
CN-115505244-A Polymer composition for making thermoformed articles 诺瓦蒙特股份公司 2022-12-23 CN claimed
US-20220372278-A1 POLYMER COMPOSITION FOR THE MANUFACTURE OF THERMOFORMED ARTICLES NOVAMONT S.P.A. (IT) 2022-11-24 US claimed
CN-110511188-B Preparation method of 2-imino dihydro quinazolinone compound 烟台大学 2022-09-20 CN claimed
US-11434363-B2 Polymer composition for the manufacture of thermoformed articles NOVAMONT S.P.A. (IT) 2022-09-06 US claimed
EP-4032953-A1 THERMOFORMED ARTICLE Novamont S.p.A. (IT) 2022-07-27 EP claimed
US-20130133676-A1 ARTIFICIAL HAIR MADE OF FLAME-RETARDANT POLYESTER KANEKA CORPORATION (JP) 2013-05-30 US claimed
WO-2013010987-A1 METHOD FOR ACTIVATING DOUBLE METAL CYANIDE CATALYSTS FOR THE PRODUCTION OF POLYETHER CARBONATE POLYOLS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-01-24 WO claimed
US-8349935-B2 Polylactic acid resin article comprising grains of metal-hydroxide particles MITSUBISHI PLASTICS, INC. (JP) 2013-01-08 US claimed
US-8211542-B2 Artificial hair made of flame-retardant polyester KANEKA CORPORATION (JP) 2012-07-03 US claimed
US-20110269878-A1 Artificial Hair Made of Flame-Retardant Polyester KANEKA CORPORATION (JP) 2011-11-03 US claimed
US-20070184264-A1 Flame-retardant polyester artificial hair KANEKA CORPORATION (JP) 2007-08-09 US claimed
US-4968777-A FIREPROOF, FLEXIBLE, STRONG POLYPLASTICS CO., LTD. (JP) 1990-11-06 US claimed
US-4128599-A MODIFIED WITH POLYCARBODIIMIDE CELANESE CORPORATION (US) 1978-12-05 US claimed
US-4071503-A THERMOPLASTIC POLYESTERS CELANESE CORPORATION (US) 1978-01-31 US claimed
US-4052360-A REINFORCED FLAME RETARDANT POLYESTER COMPOSITION HAVING NON-DRIP CHARACTERISTICS CELANESE CORPORATION (US) 1977-10-04 US claimed