Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584273 | 0.93 | CYP1A2 (0.70) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL10114668 | 0.90 | CYP1A2 (0.78) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL10114228 | 0.89 | POLB (0.81) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL10114518 | 0.89 | POLB (0.66) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL10114070 | 0.88 | CYP1A2 (0.69) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL10114064 | 0.88 | POLB (0.83) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL12584350 | 0.87 | CYP1A2 (0.78) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL10114119 | 0.85 | POLB (0.70) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL14754442 | 0.85 | CYP1A2 (0.66) | CYP1A2POLBKMT2ARXFP1TP53 | |
| SCHEMBL12584274 | 0.84 | CYP1A2 (0.74) | CYP1A2POLBKMT2ARXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093986-A1 | METHODS AND COMPOSITIONS FOR TREATING PAIN | HYDRA BIOSCIENCES, INC. (US) | 2018-04-05 | — | — | US | disclosed |
| US-8389529-B2 | Methods and compositions for treating asthma | HYDRA BIOSCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8178542-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110151018-A1 | METHODS OF INSECT CONTROL | BRANDEIS UNIVERSITY (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110151018-A1 | METHODS OF INSECT CONTROL | TRPA1, TRPV1, TRPV2 | CYP1A2 3278/4885POLB 4824/4885KMT2A 2230/4885 |
| US-20180093986-A1 | METHODS AND COMPOSITIONS FOR TREATING PAIN | ACHE, COL2A1, MMP8 | CYP1A2 2431/4885POLB 1998/4885KMT2A 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.