Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114753 | 0.99 | MLKL (0.45) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL10114707 | 0.85 | MLKL (0.52) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL10114728 | 0.83 | MEN1 (0.35) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL25129967 | 0.83 | CNR1 (0.41) | MLKLMEN1KMT2APOLBMAPT | |
| SCHEMBL10114727 | 0.82 | MEN1 (0.36) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL3142829 | 0.80 | KIF11 (0.49) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL10114722 | 0.79 | BCHE (0.50) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL14564929 | 0.78 | NPC1 (0.50) | MLKLNPC1MEN1KMT2APOLB | |
| SCHEMBL12969611 | 0.76 | CYP2C19 (0.41) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL1720160 | 0.75 | MAPT (0.44) | MAPTTP53ACHEKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722841-B2 | Carbazole novolak resin | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8674052-B2 | Carbazole novolak resin | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20130122710-A1 | CARBAZOLE NOVOLAK RESIN | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-20120077345-A1 | CARBAZOLE NOVOLAK RESIN | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-29 | — | — | US | disclosed |