Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114728 | 0.98 | MEN1 (0.35) | MEN1NPC1POLBKMT2AADRA2A | |
| SCHEMBL10114699 | 0.85 | MEN1 (0.46) | MEN1NPC1POLBKMT2AADRA2A | |
| SCHEMBL10114729 | 0.82 | MLKL (0.46) | MEN1NPC1POLBKMT2AKIF11 | |
| SCHEMBL10114753 | 0.81 | MLKL (0.45) | MEN1NPC1POLBKMT2AKIF11 | |
| SCHEMBL12888135 | 0.76 | SIGMAR1 (0.35) | MAPT | |
| SCHEMBL14564931 | 0.73 | NPC1 (0.48) | MEN1NPC1POLBKMT2AKIF11 | |
| SCHEMBL3142829 | 0.73 | KIF11 (0.49) | MEN1NPC1POLBKMT2AKIF11 | |
| SCHEMBL14564928 | 0.73 | NPC1 (0.44) | MEN1NPC1POLBKMT2AKIF11 | |
| SCHEMBL13721563 | 0.71 | SIGMAR1 (0.38) | MAPT | |
| SCHEMBL10114714 | 0.71 | NPC1 (0.48) | MEN1NPC1POLBKMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722841-B2 | Carbazole novolak resin | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8674052-B2 | Carbazole novolak resin | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20130122710-A1 | CARBAZOLE NOVOLAK RESIN | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-20120077345-A1 | CARBAZOLE NOVOLAK RESIN | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-29 | — | — | US | disclosed |