Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117881 | 0.88 | MAPK1 (0.43) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL10117510 | 0.87 | MEN1 (0.45) | FPR2KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL10117536 | 0.86 | MTOR (0.38) | KMT2AMEN1BCL2BECN1GAA | |
| SCHEMBL10117508 | 0.84 | NPC1 (0.41) | FPR2KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL10117537 | 0.82 | RAB9A (0.49) | SMN1; SMN2POLBNPC1ALDH1A1HTT | |
| SCHEMBL10117540 | 0.80 | NR1H2 (0.49) | FPR2NPC1RAB9ANR1H2 | |
| SCHEMBL10117534 | 0.76 | NR1H2 (0.40) | KMT2AMEN1MAPK1NR1H2IDO1 | |
| SCHEMBL4054860 | 0.74 | GABRG2 (0.44) | NR1H2 | |
| SCHEMBL13655228 | 0.74 | KMT2A (0.42) | KMT2ANR1H2 | |
| SCHEMBL13663124 | 0.74 | CNR2 (0.42) | KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087976-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-06-28 | — | — | WO | disclosed |