Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515643 | 0.86 | BCHE (0.55) | BCHEACHELMNATSHRCCKBR | |
| SCHEMBL10515612 | 0.86 | BCHE (0.55) | BCHEACHELMNATSHRCCKBR | |
| SCHEMBL7936445 | 0.82 | GAA (0.53) | BCHEACHEGAATSHRALDH1A1 | |
| SCHEMBL18015918 | 0.79 | HCAR2 (0.58) | GAALMNAALDH1A1 | |
| SCHEMBL1011632 | 0.79 | HDAC8 (0.57) | GAAHDAC8ADAMTS4ADAMTS5 | |
| SCHEMBL14357764 | 0.79 | HDAC8 (0.57) | GAAHDAC8ADAMTS4ADAMTS5 | |
| SCHEMBL7457787 | 0.78 | GAA (0.43) | GAAALDH1A1HDAC8ADAMTS4ADAMTS5 | |
| SCHEMBL6515372 | 0.78 | GAA (0.48) | GAALMNAALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL24103575 | 0.78 | BCHE (0.48) | BCHEACHELMNATSHRALDH1A1 | |
| SCHEMBL24103588 | 0.78 | BCHE (0.48) | BCHEACHELMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050112729-A1 | Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid | AJINOMOTO CO., INC. (JP) | 2005-05-26 | — | — | US | claimed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-10822627-B2 | Mutants of hydantoinase | EVONIK OPERATIONS GMBH (DE) | 2020-11-03 | — | — | US | disclosed |
| CN-109468304-A | The mutant of Hydantoinase | 赢创工业化学有限公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20180237814-A1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-08-23 | — | — | US | disclosed |
| US-9957536-B2 | Mutants of hydantoinase | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-01 | — | — | US | disclosed |
| EP-2780451-B1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| US-20150056667-A1 | MUTANTS OF HYDANTOINASE | EVONIK OPERATIONS GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| EP-2780451-A1 | MUTANTS OF HYDANTOINASE | Evonik Industries AG (DE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072486-A1 | MUTANTS OF HYDANTOINASE | EVONIK INDUSTRIES AG (DE) | 2013-05-23 | — | — | WO | disclosed |
| US-7314738-B2 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-20060205030-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| US-7098019-B2 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2006-08-29 | — | — | US | disclosed |
| US-20060183892-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2006-08-17 | — | — | US | disclosed |
| US-7060485-B2 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2006-06-13 | — | — | US | disclosed |
| US-20050112729-A1 | Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid | AJINOMOTO CO., INC. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1493809-A1 | RECOMBINANT DNA HAVING HYDANTOINASE GENE AND CARBAMYLASE GENE AND PROCESS FOR PRODUCING AMINO ACID | Ajinomoto Co., Inc. (JP) | 2005-01-05 | — | — | EP | disclosed |
| US-20030148472-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2003-08-07 | — | — | US | disclosed |
| US-20030113880-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | AJINOMOTO CO., INC. (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1275723-A1 | Recombinant D-hydantoin hydrolases and N-carbamyl-D-amino acid hydrolases, and DNA encoding them; uses thereof for producing D-amino acids | Ajinomoto Co., Inc. (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113880-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | DCTD, DDAH1, AHCY | BCHE 77/4885ACHE 1738/4885GAA 1461/4885 |
| US-20060205030-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | DCTD, DDAH1, AHCY | BCHE 77/4885ACHE 1738/4885GAA 1461/4885 |
| US-20030148472-A1 | DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids | DCTD, DDAH1, AHCY | BCHE 77/4885ACHE 1738/4885GAA 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.