SCHEMBL6515372

SCHEMBL6515372

O=C1NC(=O)C(COc2ccccc2)N1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
KCNA3 P22001 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.40
ADAMTS4 O75173 1/20 0.40
ADAMTS5 Q9UNA0 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CASP1 P29466 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1011756 0.78 BCHE (0.50) GAAALDH1A1LMNAADAMTS4ADAMTS5
SCHEMBL18009418 0.75 GAA (0.45) GAAALDH1A1MAPTADAMTS4ADAMTS5
SCHEMBL9770313 0.73 ALDH1A1 (0.43) ALDH1A1MAPTKCNA3LMNAMEN1
SCHEMBL7457787 0.73 GAA (0.43) GAAALDH1A1MAPTADAMTS4ADAMTS5
SCHEMBL1011632 0.73 HDAC8 (0.57) GAAADAMTS4ADAMTS5
SCHEMBL15974260 0.70 GAA (0.49) GAAALDH1A1LMNAADAMTS4ADAMTS5
SCHEMBL6791007 0.70 GAA (0.49) GAAALDH1A1LMNAADAMTS4ADAMTS5
SCHEMBL1011631 0.70 TSHR (0.43) GAAALDH1A1MAPTLMNAADAMTS4
SCHEMBL17186635 0.69 GAA (0.59) GAAALDH1A1MAPTLMNAADAMTS4
SCHEMBL12258527 0.68 HDAC8 (0.47) GAAALDH1A1LMNAADAMTS4ADAMTS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050214912-A1 Method for producing an optically active amino acid AJINOMOTO CO., INC. (JP) 2005-09-29 US disclosed