Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790127 | 1.00 | THRB (0.47) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL8840606 | 0.98 | THRB (0.46) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL25917147 | 0.95 | TSHR (0.46) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL11415318 | 0.95 | THRB (0.43) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL10300016 | 0.92 | THRB (0.53) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL725843 | 0.90 | THRB (0.52) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL4435789 | 0.89 | TSHR (0.47) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL1080732 | 0.89 | TSHR (0.47) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL7116970 | 0.86 | TSHR (0.57) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL23530292 | 0.85 | TSHR (0.55) | THRBTSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265605-B | Low-adsorption salt-resistant resistance-reducing agent suitable for shale reservoir fracturing transformation | 西南石油大学 | 2020-12-04 | — | — | CN | claimed |
| US-4745097-A | SUBBING LAYER, CATIONIC POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-17 | — | — | US | claimed |
| EP-0039564-B1 | ELECTROCONDUCTIVE POLYMER COMPOSITIONS | CALGON CORPORATION (US) | 1984-10-31 | — | — | EP | claimed |
| US-4306996-A | POLYDIMETHYLSILOXANE AND A CATIONIC POLYMER | CALGON CORPORATION (US) | 1981-12-22 | — | — | US | claimed |
| EP-0039564-A1 | Electroconductive polymer compositions | CALGON CORPORATION (US) | 1981-11-11 | — | — | EP | claimed |
| US-4259411-A | CONDUCTIVE COATING OVER BARRIER COATING | CALGON CORPORATION (US) | 1981-03-31 | — | — | US | claimed |
| EP-0012517-A1 | Electroconductive articles and a method of preparing them | CALGON CORPORATION (US) | 1980-06-25 | — | — | EP | claimed |
| US-11173106-B2 | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener | JOHNSON & JOHNSON CONSUMER INC. (US) | 2021-11-16 | — | — | US | disclosed |
| CN-109265605-B | Low-adsorption salt-resistant resistance-reducing agent suitable for shale reservoir fracturing transformation | 西南石油大学 | 2020-12-04 | — | — | CN | disclosed |
| EP-3401730-B1 | LENTICULAR SHEET, LENTICULAR PRINTED ARTICLE, AND METHOD FOR MANUFACTURING LENTICULAR PRINTED ARTICLE | FUJIFILM CORP (JP) | 2020-03-04 | — | — | EP | disclosed |
| US-10379264-B2 | Lenticular sheet, lenticular printed material, and method of producing lenticular printed material | FUJIFILM CORPORATION (JP) | 2019-08-13 | — | — | US | disclosed |
| US-20180335550-A1 | LENTICULAR SHEET, LENTICULAR PRINTED MATERIAL, AND METHOD OF PRODUCING LENTICULAR PRINTED MATERIAL | FUJIFILM CORPORATION (JP) | 2018-11-22 | — | — | US | disclosed |
| EP-3401730-A1 | LENTICULAR SHEET, LENTICULAR PRINTED ARTICLE, AND METHOD FOR MANUFACTURING LENTICULAR PRINTED ARTICLE | FUJIFILM Corporation (JP) | 2018-11-14 | — | — | EP | disclosed |
| US-4734395-A | CATIONIC SIZING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0039564-B1 | ELECTROCONDUCTIVE POLYMER COMPOSITIONS | CALGON CORPORATION (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4446174-A | Method of ink-jet recording | Fuiji Photo Film Company, Ltd. (JP) | 1984-05-01 | — | — | US | disclosed |
| US-4306996-A | POLYDIMETHYLSILOXANE AND A CATIONIC POLYMER | CALGON CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| EP-0039564-A1 | Electroconductive polymer compositions | CALGON CORPORATION (US) | 1981-11-11 | — | — | EP | disclosed |
| US-4259411-A | CONDUCTIVE COATING OVER BARRIER COATING | CALGON CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| EP-0012517-A1 | Electroconductive articles and a method of preparing them | CALGON CORPORATION (US) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11173106-B2 | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener | ABHD16A, DSG1, CUTA | CHRM1 2675/4885CHRM3 1958/4885CHRM2 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.