Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117572 | 0.83 | S100B (0.43) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL19980897 | 0.82 | HDAC1 (0.40) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL19903974 | 0.79 | S100B (0.55) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL14679866 | 0.78 | THRB (0.43) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL21117538 | 0.78 | BTK (0.37) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL19980984 | 0.77 | HDAC1 (0.40) | THRBALDH1A1TP53KDM4EGAA | |
| SCHEMBL19980955 | 0.77 | HDAC1 (0.38) | TSHRALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10119249 | 0.77 | MYC (0.40) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL18633372 | 0.76 | THRB (0.37) | THRBTSHRHPGDMAPTKDM4E | |
| SCHEMBL14341772 | 0.76 | THRB (0.43) | THRBTSHRALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |