Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119337 | 0.75 | ADRB1 (0.36) | HDAC1FPR3FPR2CYP3A4EPHX2 | |
| SCHEMBL873706 | 0.73 | PFKFB2 (0.42) | SCN3ASCN9AHDAC3HDAC4HDAC1 | |
| SCHEMBL845510 | 0.72 | SCN3A (0.54) | SCN3ASCN9AHDAC3HDAC4HDAC1 | |
| SCHEMBL871886 | 0.72 | SCN3A (0.39) | SCN3ASCN9AHDAC3HDAC4HDAC1 | |
| SCHEMBL845190 | 0.71 | EPHX2 (0.42) | MEN1NPC1RAB9AKMT2AFPR3 | |
| Hydrochloric Acid SCHEMBL16741983 | 0.71 | SCN3A (0.52) | SCN3ASCN9AHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL16741981 | 0.71 | SCN3A (0.52) | SCN3ASCN9AHDAC3HDAC4HDAC1 | |
| SCHEMBL873383 | 0.69 | CHRNA7 (0.36) | HDAC1KMT2AFPR3FPR2 | |
| SCHEMBL10119480 | 0.69 | GAA (0.39) | SCN3ASCN9AHDAC3HDAC4HDAC1 | |
| SCHEMBL845086 | 0.69 | EPHX2 (0.40) | MEN1NPC1RAB9AKMT2AFPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |