Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119337 | 0.87 | ADRB1 (0.36) | CHRNA7NAMPTFPR3FPR2HDAC1 | |
| SCHEMBL845351 | 0.84 | ITGB1 (0.41) | CHRNA7KMT2ANAMPTCYP17A1CYP21A2 | |
| SCHEMBL845622 | 0.80 | ITGB1 (0.42) | CHRNA7NAMPTALDH1A1HTTTHRB | |
| SCHEMBL845097 | 0.78 | NAMPT (0.39) | KMT2ANAMPTALDH1A1HTT | |
| SCHEMBL845098 | 0.75 | ITGB1 (0.43) | KMT2AALDH1A1HTTHDAC1 | |
| SCHEMBL845334 | 0.74 | ITGB1 (0.39) | CHRNA7KMT2ANAMPTHDAC1 | |
| SCHEMBL872288 | 0.73 | ITGB1 (0.37) | CHRNA7NAMPT | |
| SCHEMBL845086 | 0.71 | EPHX2 (0.40) | KMT2AFPR3FPR2ALDH1A1 | |
| SCHEMBL10119509 | 0.70 | PAX8 (0.35) | CHRNA7NAMPTTHRB | |
| SCHEMBL845099 | 0.70 | ITGB1 (0.44) | KMT2AALDH1A1HTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |