SCHEMBL10121157

SCHEMBL10121157

CC1(C)OC(C)(C)C(O)=C(c2cc(-c3ccc(Cl)cc3Cl)ccc2C2CC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.39
EDNRA P25101 1/20 0.39
PTGS2 P35354 1/20 0.37
CNR1 P21554 13/20 0.35
CNR2 P34972 13/20 0.35
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 7/20 0.35
ABCB1 P08183 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435275 1.00 EDNRB (0.39) EDNRBEDNRAPTGS2CNR1CNR2
SCHEMBL29538786 0.90 FASN (0.35)
SCHEMBL10121135 0.90 FASN (0.35)
SCHEMBL12128952 0.89 ACACB (0.38) EDNRBEDNRASLC6A3ALDH1A1MAPT
SCHEMBL29642949 0.85 EDNRB (0.42) EDNRBEDNRAPTGS2CNR1CNR2
SCHEMBL29384538 0.84 EDNRB (0.39) EDNRBEDNRAPTGS2CNR1CNR2
SCHEMBL29435263 0.84 SLC6A3 (0.44) EDNRBEDNRAPTGS2CNR1CNR2
SCHEMBL15484261 0.84 EDNRB (0.39) EDNRBEDNRAPTGS2CNR1CNR2
SCHEMBL28337836 0.84 SLC6A3 (0.44) EDNRBEDNRAPTGS2CNR1CNR2
SCHEMBL12129064 0.84 ACACB (0.40) EDNRBEDNRAPTGS2CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof BASF Agro B.V. (NL) 2025-08-05 US claimed
EP-3568016-B1 MICROCAPSULES COMPRISING CINMETHYLIN IN THE CORE AND A POLYUREA DERIVED FROM DIPHENYLMETHANE DIISOCYANATE OR AN OLIGOMER THEREOF BASF AGRO BV (NL) 2024-07-17 EP claimed
WO-2024012905-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2024-01-18 WO claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 US claimed
EP-3957176-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS, HERBICIDAL COMPOSITION AND METHOD FOR CONTROLLING UNDESIRABLE VEGETATION BASF Agro B.V. (NL) 2022-02-23 EP claimed
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) BASF SE (DE) 2021-05-20 US claimed
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2021-05-06 US claimed
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2021-03-25 US claimed
EP-3723485-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2020-10-21 EP claimed
WO-2018130588-A1 COMPOSITION COMPRISING CINMETHYLIN-CONTAINING MICROPARTICLES AND A FURTHER HERBICIDE BASF Agro B.V. (NL) 2018-07-19 WO claimed
US-9999222-B2 Herbicidal combination comprising azines BASF SE (DE) 2018-06-19 US claimed
WO-2017153200-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-09-14 WO claimed
WO-2017137351-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-17 WO claimed
EP-3205208-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-16 EP claimed
EP-3133920-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-03-01 EP claimed
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-02-16 US claimed
US-20150342193-A1 Herbicidal Composition BASF SE (DE) 2015-12-03 US claimed
WO-2015162164-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2015-10-29 WO claimed
WO-2014102069-A1 HERBICIDAL COMPOSITION BASF SE (DE) 2014-07-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150342193-A1 Herbicidal Composition DDT, AS3MT, ACHE EDNRB 3378/4885EDNRA 3512/4885PTGS2 3813/4885
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH EDNRB 3894/4885EDNRA 3916/4885PTGS2 3576/4885
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, TH EDNRB 3894/4885EDNRA 3916/4885PTGS2 3576/4885
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) GLO1, DDT, GMDS EDNRB 3147/4885EDNRA 2097/4885PTGS2 277/4885
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES TH, CASP3, PIK3C3 EDNRB 4498/4885EDNRA 4245/4885PTGS2 3826/4885
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS CBR3, CBR1, DDT EDNRB 3970/4885EDNRA 4024/4885PTGS2 4168/4885
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES CBR3, CBR1, DDT EDNRB 1682/4885EDNRA 1402/4885PTGS2 3125/4885
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof NCL, PNN, DBN1 EDNRB 1783/4885EDNRA 1203/4885PTGS2 3049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.