SCHEMBL10122747

SCHEMBL10122747

Brc1c2ccccc2cc2c1oc1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.47
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HSD17B10 Q99714 2/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
ALOX5 P09917 2/20 0.38
MAOA P21397 3/20 0.38
POLB P06746 1/20 0.37
DYRK1A Q13627 1/20 0.37
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
PGAM1 P18669 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30808544 1.00 AHR (0.47) AHRALDH1A1KDM4EMAPTHPGD
SCHEMBL28157069 0.86 GABRP (0.41) AHRKDM4EMAPTHPGDMEN1
SCHEMBL17383076 0.81 HSD17B10 (0.44) AHRALDH1A1KDM4EMAPTHPGD
SCHEMBL26266197 0.80 AHR (0.46) AHRSMN1; SMN2CYP1B1MAOACYP1A2
SCHEMBL21234340 0.79 LOXL2 (0.39) AHRALDH1A1HPGDKMT2AHSD17B10
SCHEMBL24155724 0.78 AHR (0.66) AHRALDH1A1KDM4EMAPTHPGD
SCHEMBL10122689 0.78 AHR (0.47) AHRALDH1A1KDM4EMAPTHPGD
SCHEMBL16283915 0.78 AHR (0.47) AHRALDH1A1KDM4EMAPTHPGD
SCHEMBL10147421 0.78 AHR (0.47) AHRALDH1A1KDM4EMAPTHPGD
SCHEMBL18271546 0.77 MAOB (0.47) AHRSMN1; SMN2NPC1RAB9AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10014481-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-03 US disclosed
US-20170054086-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054086-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-9373792-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-9373792-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
EP-2436679-B1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO (JP) 2016-01-06 EP disclosed
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2015-12-24 US disclosed
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2015-12-24 US disclosed
US-9147847-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-29 US disclosed
US-9147847-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-29 US disclosed
US-20150005512-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-01-01 US disclosed
US-8866135-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-10-21 US disclosed
US-8866135-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-10-21 US disclosed
US-20140159005-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IIDEMITSU KOSAN CO., LTD (JP) 2014-06-12 US disclosed
US-20140159005-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IIDEMITSU KOSAN CO., LTD (JP) 2014-06-12 US disclosed
US-8629430-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-14 US disclosed
US-8629430-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-14 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
WO-2010137285-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME 出光興産株式会社 (JP) 2010-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10014481-B2 Compound and organic light-emitting device including the same ALDH1A2, AOX1, O60361 AHR 4332/4885ALDH1A1 11/4885KDM4E 2650/4885
US-20140159005-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 AHR 314/4885ALDH1A1 364/4885KDM4E 2002/4885
US-20170054086-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ALDH1A2, AOX1, O60361 AHR 4332/4885ALDH1A1 11/4885KDM4E 2650/4885
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 AHR 314/4885ALDH1A1 364/4885KDM4E 2002/4885
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 AHR 314/4885ALDH1A1 364/4885KDM4E 2002/4885
US-20150005512-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 AHR 314/4885ALDH1A1 364/4885KDM4E 2002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.