SCHEMBL10123836

SCHEMBL10123836

CCc1ccc2c(c1)c1cc(CC)ccc1n2-c1ccc(N(c2ccccc2)c2ccc(/C=C/c3ccc(N(c4ccccc4)c4ccc(-n5c6ccc(CC)cc6c6cc(CC)ccc65)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.38
PGR P06401 1/20 0.36
RORA P35398 1/20 0.36
RORC P51449 1/20 0.36
RORB Q92753 1/20 0.36
RELA Q04206 1/20 0.36
PLA2G4A P47712 1/20 0.35
ALOX5 P09917 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPK1 P28482 2/20 0.34
ATM Q13315 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
USP2 O75604 2/20 0.34
CTNNB1 P35222 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123765 0.99 RELA (0.39) APPPGRRORARORCRORB
SCHEMBL10123704 0.95 APP (0.37) APPPGRRORARORCRORB
SCHEMBL10123630 0.94 RELA (0.37) APPPGRRORARORCRORB
SCHEMBL10123776 0.88 APP (0.44) APPRELAALOX5PTGS1PTGS2
SCHEMBL12704956 0.88 PGR (0.39) PGRRORARORCRORBRELA
SCHEMBL10123840 0.88 RORA (0.39) APPPGRRORARORCRORB
SCHEMBL10123642 0.88 KDM4E (0.42) APPRELAPLA2G4AALOX5PTGS1
SCHEMBL10123768 0.87 RORA (0.38) APPPGRRORARORCRORB
SCHEMBL13620176 0.87 PTGES (0.39) PGRRORARORCRORBRELA
SCHEMBL12704849 0.87 PTGES (0.39) PGRRORARORCRORBRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
EP-1931634-B1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-11-09 EP disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-11 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device NR0B1, NR2E3, NR0B2 APP 3044/4885PGR 347/4885RORA 132/4885
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability NR0B1, TERB1, CYP1B1 APP 4087/4885PGR 340/4885RORA 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.