Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012509 | 1.00 | PDE10A (0.46) | PDE10AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1011709 | 0.80 | PDE10A (0.53) | PDE10AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18434428 | 0.79 | PDE10A (0.51) | PDE10AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31570753 | 0.79 | PDE10A (0.51) | PDE10AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1710123 | 0.78 | TSHR (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1595062 | 0.78 | TSHR (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13602996 | 0.78 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11997107 | 0.76 | LMNA (0.41) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7749765 | 0.75 | NPC1 (0.38) | PDE10AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1011432 | 0.74 | TSHR (0.56) | PDE10AMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| US-9102688-B2 | Sulfonaminoquinoline hepcidin antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2014-12-11 | — | — | US | disclosed |
| US-20120214803-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
| EP-1955384-B1 | ELECTROLUMINESCENT DEVICE CONTAINING AN ANTHRACENE DERIVATIVE | GLOBAL OLED TECHNOLOGY LLC (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-1955385-B1 | ELECTROLUMINESCENT DEVICE CONTAINING A PHENANTHROLINE DERIVATIVE | GLOBAL OLED TECHNOLOGY LLC (US) | 2011-01-05 | — | — | EP | disclosed |
| US-7553558-B2 | Electroluminescent device containing an anthracene derivative | EASTMAN KODAK COMPANY (US) | 2009-06-30 | — | — | US | disclosed |
| EP-1955384-A1 | ELECTROLUMINESCENT DEVICE CONTAINING AN ANTHRACENE DERIVATIVE | EASTMAN KODAK COMPANY (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1955385-A2 | ELECTROLUMINESCENT DEVICE CONTAINING A PHENANTHROLINE DERIVATIVE | EASTMAN KODAK COMPANY (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007064484-A2 | ELECTROLUMINESCENT DEVICE CONTAINING A PHENANTHROLINE DERIVATIVE | EASTMAN KODAK COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007064493-A1 | ELECTROLUMINESCENT DEVICE CONTAINING AN ANTHRACENE DERIVATIVE | EASTMAN KODAK COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| US-20070122656-A1 | Electroluminescent device containing an anthracene derivative | EASTMAN KODAK COMPANY | 2007-05-31 | — | — | US | disclosed |
| US-20070122657-A1 | Electroluminescent device containing a phenanthroline derivative | EASTMAN KODAK COMPANY | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214803-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | HAMP, SLC40A1, FTH1 | PDE10A 3260/4885MAPT 4801/4885MEN1 2680/4885 |
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | HAMP, SLC40A1, FTH1 | PDE10A 3260/4885MAPT 4801/4885MEN1 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.